Virology articles from across Nature Portfolio

Virology is the scientific discipline concerned with the study of the biology of viruses and viral diseases, including the distribution, biochemistry, physiology, molecular biology, ecology, evolution and clinical aspects of viruses.

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News & Views | 03 May 2023

Structure of the most abundant human gut virus

Nature

Latest Research and Reviews

Research
31 May 2023 | Open Access

A pan-influenza antibody inhibiting neuraminidase via receptor mimicry

The neuraminidase-targeting monoclonal antibody FNI9 potently inhibits the enzymatic activity of influenza A and B viruses via receptor mimicry.
- Corey Momont
- , Ha V. Dang
- & Matteo Samuele Pizzuto
Nature, 1-8
Research
31 May 2023 | Open Access

Selection and validation of reference genes for RT-qPCR normalization of porcine alveolar macrophages (PAMs) for PRRSV studies
- Dayoung Oh
- , Ward De Spiegelaere
- & Hans J. Nauwynck
Scientific Reports 13, 8840
Research
30 May 2023 | Open Access

Design of bacteriophage T4-based artificial viral vectors for human genome remodeling

Safe delivery of genes is needed for gene therapy. Here the authors build “artificial viral vectors” (AVVs) by engineering the well-characterised structural components of bacteriophage T4: the large capacity, all-in-one, multiplex, programmable, and phage-based AVV nanomaterials have potential for gene therapy.
- Jingen Zhu
- , Himanshu Batra
- & Venigalla B. Rao
Nature Communications 14, 2928
Research
29 May 2023 | Open Access

Highly lethal genotype I and II recombinant African swine fever viruses detected in pigs

Potential recombination of African swine fever virus genotypes is not well understood. Here, Zhao et al. report naturally occurring ASFVs carrying mosaic genomes of genotype I and II and show that the recombinant virus is lethal in pigs and evades the immunity induced by genotype II live vaccine.
- Dongming Zhao
- , Encheng Sun
- & Zhigao Bu
Nature Communications 14, 3096
Research
29 May 2023 | Open Access

Rapid evolution of A(H5N1) influenza viruses after intercontinental spread to North America

Highly pathogenic avian influenza A(H5N1) viruses of clade 2.3.4.4b underwent an explosive geographic expansion in 2021 among wild birds and domestic poultry. Here, Kandeil et al. show that the Western movement of this clade was followed by reassortment with viruses circulating in wild birds in North America which resulted in different genotypes exhibiting a wide range of disease severity in mammal models (mice, ferrets, chicken) ranging from asymptomatic disease to severe neurological pathology.
- Ahmed Kandeil
- , Christopher Patton
- & Richard J. Webby
Nature Communications 14, 3082
Research
29 May 2023 | Open Access

Fibroblasts are a site of murine cytomegalovirus lytic replication and Stat1-dependent latent persistence in vivo

Fibroblasts are an established cell type permissive for cytomegalovirus infection. Here the authors identify a population of fibroblast cells that can support murine cytomegalovirus lytic and latent virus infection in vivo and propose STAT1 as critically involved in murine cytomegalovirus latency.
- Katarzyna M. Sitnik
- , Fran Krstanović
- & Luka Čičin-Šain
Nature Communications 14, 3087

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News and Comment

News | 26 May 2023

US will vaccinate birds against avian flu for first time — what researchers think

The country plans to vaccinate endangered condors in an effort to curb unprecedented H5N1 outbreaks.
- Max Kozlov
Nature
Comments & Opinion | 25 May 2023

Coordinated surveillance is essential to monitor and mitigate the evolutionary impacts of SARS-CoV-2 spillover and circulation in animal hosts

SARS-CoV-2 lineages circulating in animal reservoirs may broaden the evolutionary potential of the virus and increase the risk of novel variants emerging. There is an urgent need for more-comprehensive surveillance of SARS-CoV-2 circulating in nonhuman hosts.
- Suresh V. Kuchipudi
- , Cedric Tan
- & Francois Balloux
Nature Ecology & Evolution, 1-4
News | 17 May 2023

Why is COVID life-threatening for some people? Genetics study offers clues

Immune genes could play a part in the risk of needing intensive care when infected with SARS-CoV-2.
- Heidi Ledford
Nature 617, 661-662
News | 08 May 2023

NIH reinstates grant for controversial coronavirus research

EcoHealth Alliance lost funding during the Trump administration, but can now proceed with its research — under extensive restrictions.
- Max Kozlov
Nature 617, 449
News | 05 May 2023

WHO declares end to COVID-19’s emergency phase

The pandemic has been on a “downward trend”, but the risk of new variants remains, says WHO director-general.
- Mariana Lenharo
Nature
News | 05 May 2023

CDC director Rochelle Walensky is leaving her post

Chief of US public-health agency announced her departure as COVID-19 emergency declarations end.
- Traci Watson
- & Max Kozlov
Nature

All News & Comment

Virology articles from across Nature Portfolio

Featured

Structure of the most abundant human gut virus

Latest Research and Reviews

A pan-influenza antibody inhibiting neuraminidase via receptor mimicry

Selection and validation of reference genes for RT-qPCR normalization of porcine alveolar macrophages (PAMs) for PRRSV studies

Design of bacteriophage T4-based artificial viral vectors for human genome remodeling

Highly lethal genotype I and II recombinant African swine fever viruses detected in pigs

Rapid evolution of A(H5N1) influenza viruses after intercontinental spread to North America

Fibroblasts are a site of murine cytomegalovirus lytic replication and Stat1-dependent latent persistence in vivo

News and Comment

US will vaccinate birds against avian flu for first time — what researchers think

Coordinated surveillance is essential to monitor and mitigate the evolutionary impacts of SARS-CoV-2 spillover and circulation in animal hosts

Why is COVID life-threatening for some people? Genetics study offers clues

NIH reinstates grant for controversial coronavirus research

WHO declares end to COVID-19’s emergency phase

CDC director Rochelle Walensky is leaving her post

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