Viral immune evasion articles from across Nature Portfolio

Viral immune evasion is the process by which viruses evade the immune system of the host. Viruses use diverse mechanisms to avoid and antagonize the immune response of their hosts.

Latest Research and Reviews

News and Comment

  • News & Views |

    New work from Udeochu, Amin, Huang, and colleagues provides mechanistic insights into how the tau protein engages the cGAS–STING pathway to elicit antiviral responses in Alzheimer’s disease. This signaling axis diminishes the MEF2C transcriptional network in neurons critical for maintaining cognitive function.

    • Andrea Francesca M. Salvador
    •  & Jonathan Kipnis
    Nature Immunology 24, 741-742
  • Comments & Opinion |

    The comparatively milder infections with the Omicron variant and higher levels of population immunity have raised hopes for a weakening of the pandemic. We argue that the lower severity of Omicron is a coincidence and that ongoing rapid antigenic evolution is likely to produce new variants that may escape immunity and be more severe.

    • Peter V. Markov
    • , Aris Katzourakis
    •  & Nikolaos I. Stilianakis
  • News & Views |

    On 15–16 November 2021, the National Institute of Allergy and Infectious Diseases (NIAID), the National Cancer Institute (NCI) and the National Heart, Lung, and Blood Institute (NHLBI) hosted a virtual workshop on DEAD/DEAH-box RNA helicases in health and disease. The goal of the workshop was to review current advances, and identify knowledge gaps and future research to improve our understanding of the function of RNA helicases, and leverage these molecules as molecular targets with translational potential.

    • Ourania Andrisani
    • , Qian Liu
    •  & Michael Gale Jr
    Nature Immunology 23, 354-357
  • News & Views |

    Analysis of the whole-genome transcriptional activity of HIV-specific CD4+ T cells demonstrates distinct profiles associated with natural control of HIV replication, as well as dysfunctional phenotypes that persist even after effective antiretroviral therapy.

    • Celine Gubser
    • , Matthew C Pitman
    •  & Sharon R. Lewin
    Nature Immunology 20, 948-950