Featured
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News |
One antibody to bind them all
An antibody that recognizes all strains of influenza A could be a universal vaccine blueprint.
- Marian Turner
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Research Highlights |
Mix-and-match for meningitis
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Research Highlights |
Crystal ball for flu vaccines
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Outlook |
Vaccines: Chasing the dream
After a decade of disappointments, hopes for a successful Alzheimer's vaccine that ameliorates symptoms and ultimately prevents the disease are rising again.
- Jim Schnabel
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News |
Vaccine trial's ethics criticized
Collapsed trial fuels unfounded vaccine fears.
- Priya Shetty
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News Q&A |
Vaccines warrant firm focus
Diseases such as malaria and HIV still present a major challenge to vaccine development, says Gates foundation's departing global-health chief.
- Erika Check Hayden
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Outlook |
Vaccines: A moving target
The hepatitis C virus has a set of cunning ways to evade immunity, but researchers are turning the immune system on it.
- Michael Eisenstein
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News |
Hepatitis C mouse model a major milestone
Development paves the way for testing potential vaccines.
- Virginia Gewin
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Comment |
Lessons from polio eradication
Ridding the world of polio requires a global initiative that tailors strategies to communities, say Heidi J. Larson and Isaac Ghinai.
- Heidi J. Larson
- & Isaac Ghinai
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Comment |
Target the fence-sitters
Past waves of vaccine rejection in industrialized nations have a lot to teach us about preventing future ones, argues Julie Leask.
- Julie Leask
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News & Views |
Persistence pays off
Developing AIDS vaccines has been a frustrating business. A vaccine that triggers immune responses that effectively control early infection by the simian counterpart of HIV in macaques seems promising. See Letter p.523
- R. Paul Johnson
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News Feature |
Vaccines: The real issues in vaccine safety
Hysteria about false vaccine risks often overshadows the challenges of detecting the real ones.
- Roberta Kwok
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Perspective |
A 2020 vision for vaccines against HIV, tuberculosis and malaria
- Rino Rappuoli
- & Alan Aderem
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Letter |
Detection of prokaryotic mRNA signifies microbial viability and promotes immunity
- Leif E. Sander
- , Michael J. Davis
- & J. Magarian Blander
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News |
WHO to decide fate of smallpox stocks
Heated debate expected next week over when to destroy lab samples of deadly virus.
- Declan Butler
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Letter |
Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine
- Scott G. Hansen
- , Julia C. Ford
- & Louis J. Picker
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Feature |
Cancer research: Promise of protection
Cancer vaccines have long shown lots of potential but few results. Signs of success now suggest opportunities.
- Kelly Rae Chi
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Outlook |
Vaccines: Know your enemy
Vaccines are arguably our greatest medical achievement. But to what extent can they help prevent cancer?
- Michael Eisenstein
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News |
Pneumococcal vaccine rolls out in developing world
Vaccine is first to be launched in rich and poor countries simultaneously.
- Anjali Nayar
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Research Highlights |
TB vaccine with a long view
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Books & Arts |
Epidemiology: Epidemic of panic
Autism's broad diagnosis has fuelled fears about vaccines despite no evidence for a link, finds Melvin Konner.
- Melvin Konner
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News |
Cholera vaccine plan splits experts
Opinion is divided over how to tackle the disease in Haiti.
- David Cyranoski
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News |
Vaccine offers meningitis hope
First affordable and effective weapon against killer meningococcal meningitis A rolled out in Africa.
- Declan Butler
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News |
Strategy to fight HIV shapes up
A way to nail down the shape of a viral protein segment could spur vaccine development.
- Alla Katsnelson
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News |
Statistics spark dismissal suit
Fired researcher's allegations of misconduct prompt university to investigate vaccine trial.
- Emma Marris
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News |
Therapeutic HIV vaccines show promise
Clinical trials hint that treatment strategy is not a dead end.
- Alison Abbott
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Outlook |
Tiny steps towards an HIV vaccine
Recent successes are reinvigorating research into a vaccine for HIV, reports Cassandra Willyard.
- Cassandra Willyard
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News |
Souped-up antibody fends off HIV
Targeted search yields proteins that neutralize nearly all HIV strains.
- Heidi Ledford
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News |
Flu experts rebut conflict claims
Reports throw unsubstantiated suspicion on scientific advice given to the World Health Organization.
- Declan Butler
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News |
Well-trained immune cells keep HIV in check
Differences in T-cell development may explain why some infected people do not develop AIDS.
- Alla Katsnelson
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News |
A shot in the arm for cancer vaccines?
Researchers anxiously await a decision by US regulators on a controversial cancer therapy.
- Heidi Ledford
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News |
How 1918 flu antibodies fend off swine flu
Structural similarities reveal why some elderly people were spared in the recent pandemic.
- Heidi Ledford
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Opinion |
Accelerating HIV vaccine development
Translational-research programmes supported by flexible, long-term, large-scale grants are needed to turn advances in basic science into successful vaccines to halt the AIDS epidemic, says Wayne C. Koff.
- Wayne C. Koff
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News |
Ten billion dollars pledged for 'decade of vaccines'
Gates Foundation cash could save nearly nine million children.
- Heidi Ledford