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Article
| Open AccessAnti-angiogenic therapy using the multi-tyrosine kinase inhibitor Regorafenib enhances tumor progression in a transgenic mouse model of ß-cell carcinogenesis
- Maren Juliane Egidi
- , Sebastian Krug
- & Heidi Griesmann
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Nicardipine is a putative EED inhibitor and has high selectivity and potency against chemoresistant prostate cancer in preclinical models
- Xin Li
- , Yanhua Chen
- & Daqing Wu
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Review Article |
Rethinking our approach to cancer metabolism to deliver patient benefit
- Saverio Tardito
- & Craig MacKay
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Article
| Open AccessIn silico enhancer mining reveals SNS-032 and EHMT2 inhibitors as therapeutic candidates in high-grade serous ovarian cancer
- Marcos Quintela
- , David W. James
- & Lewis W. Francis
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Article
| Open AccessMorpholino-driven blockade of Dkk-1 in osteosarcoma inhibits bone damage and tumour expansion by multiple mechanisms
- Simin Pan
- , Michael Cesarek
- & Carl A. Gregory
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Preclinical study of 212Pb alpha-radioimmunotherapy targeting CD20 in non-Hodgkin lymphoma
- Stéphanie Durand-Panteix
- , Jacques Monteil
- & Isabelle Quelven
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Review Article
| Open AccessUCHL1 as a novel target in breast cancer: emerging insights from cell and chemical biology
- Milon Mondal
- , Daniel Conole
- & Edward W. Tate
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Targeting the actin/tropomyosin cytoskeleton in epithelial ovarian cancer reveals multiple mechanisms of synergy with anti-microtubule agents
- Xing Xu
- , Yao Wang
- & Peter W. Gunning
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Article
| Open AccessPharmacological blockage of transforming growth factor-β signalling by a Traf2- and Nck-interacting kinase inhibitor, NCB-0846
- Teppei Sugano
- , Mari Masuda
- & Tesshi Yamada
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Article
| Open AccessEnhanced antitumor effect of binimetinib in combination with capecitabine for biliary tract cancer patients with mutations in the RAS/RAF/MEK/ERK pathway: phase Ib study
- Jin Won Kim
- , Kyung-Hun Lee
- & Do-Youn Oh
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Mini Review
| Open AccessLysophosphatidic acid production and action: critical new players in breast cancer initiation and progression
- N Panupinthu
- , H Y Lee
- & G B Mills