Featured
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Brief Communication |
Label-free metabolic imaging by mid-infrared optoacoustic microscopy in living cells
Mid-infrared optoacoustic microscopy enables label-free, bond-selective imaging in living cells
- Miguel A. Pleitez
- , Asrar Ali Khan
- & Vasilis Ntziachristos
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News Feature |
Technology comes to typing
As mass spectrometry makes inroads into pathogen identification in the clinical laboratory, deep sequencing—even nanopore sequencing—is waiting in the wings. Jeffrey L. Fox investigates.
- Jeffrey L Fox
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Correspondence |
A cross-platform toolkit for mass spectrometry and proteomics
- Matthew C Chambers
- , Brendan Maclean
- & Parag Mallick
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News & Views |
Streamlining biomarker discovery
Integrating targeted mass spectrometry into proteomic pipelines speeds the validation of disease biomarkers.
- Martin Latterich
- & Jan E Schnitzer
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News & Views |
A new look at membrane protein binding
An optical spectroscopy method can measure the affinities of ligands to membrane receptors that are embedded in their native membranes.
- Charles A Lunn
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Correspondence |
ProHits: integrated software for mass spectrometry–based interaction proteomics
- Guomin Liu
- , Jianping Zhang
- & Anne-Claude Gingras
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Perspective |
Options and considerations when selecting a quantitative proteomics strategy
- Bruno Domon
- & Ruedi Aebersold
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News & Views |
Enriching quantitative proteomics with SIN
A new metric called the normalized spectral index (SIN) provides a simple way to quantify and compare label-free proteomics data.
- Mihaela E Sardiu
- & Michael P Washburn
Prediction of single-cell RNA expression profiles in live cells by Raman microscopy with Raman2RNA