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Volume 42 Issue 3, March 2024

Point-of-care monitoring

A miniaturized ultrasonic system can provide full-body monitoring and diagnosis. Lin et al. engineer a soft, wireless ultrasound device to measure deep body signals in moving subjects, offering a hands-free solution for continuous, comprehensive health tracking at the point of care.

See Lin et al.

Image: Muyang Lin, University of California San Diego. Cover design: Erin Dewalt.

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  • The fusion of a programmable transcription-activator-like effector (TALE) protein with a nickase, in conjunction with a deaminase, enables efficient and strand-selective DNA base editing. This approach has the potential to advance our understanding and treatment of diseases associated with mutations in the mitochondrial or nuclear genome.

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