Featured
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Article |
Multiple dynamic representations in the motor cortex during sensorimotor learning
Genetically encoded neural activity markers were used in mice to simultaneously follow large populations of motor cortex neurons during sensorimotor learning, revealing that spatially intermingled neurons represent either sensory or motor behaviour, with population-level representations of subsets of motor programs strengthening as training progressed.
- D. Huber
- , D. A. Gutnisky
- & K. Svoboda
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News & Views |
The symphony of choice
The brain's parietal cortex seems to orchestrate decision-making without single neurons performing 'solos'. Rather, decision-specific motifs emerge as highly organized sequences of short-lived neuronal activity. See Article p.62
- Eduardo Dias-Ferreira
- & Rui M. Costa
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News |
Rejected flies turn to booze
Single neurotransmitter underlies rewards from sex and alcohol.
- Ed Yong
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News & Views |
Reward alters specific connections
How does the brain couple a fleeting sensory input to a delayed reward during learning? A study in locusts shows that coincident firing of neurons can 'mark' a neuronal connection for later modulation. See Article p.47
- Timothy E. Holy
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Letter |
Neuron-type-specific signals for reward and punishment in the ventral tegmental area
Dopaminergic neurons in the mouse ventral tegmental area signal the difference between received and expected reward, whereas GABAergic neurons signal expected reward.
- Jeremiah Y. Cohen
- , Sebastian Haesler
- & Naoshige Uchida
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Letter |
Verbal and non-verbal intelligence changes in the teenage brain
- Sue Ramsden
- , Fiona M. Richardson
- & Cathy J. Price
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Letter |
Primary motor cortex underlies multi-joint integration for fast feedback control
- J. Andrew Pruszynski
- , Isaac Kurtzer
- & Stephen H. Scott
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Letter |
Neural network computation with DNA strand displacement cascades
- Lulu Qian
- , Erik Winfree
- & Jehoshua Bruck
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Article |
Support for a synaptic chain model of neuronal sequence generation
When songbirds sing, neurons in premotor areas fire coordinated bursts precisely timed to the dynamics of the song. The cellular mechanism for such sequence generation is unknown. These authors make the technical breakthrough of recording intracellularly in HVC neurons in singing birds, allowing them to test models of burst generation. They found that membrane potential rapidly depolarizes 5–10 ms before burst onset, consistent with models in which HVC neurons form synaptically connected chains.
- Michael A. Long
- , Dezhe Z. Jin
- & Michale S. Fee
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Research Highlights |
Psychology: Gaming the brain