Operant learning articles within Nature

Featured

• Article
  13 December 2023 | Open Access

  Dynamic behaviour restructuring mediates dopamine-dependent credit assignment

  Initial dopamine self-stimulations reinforced not only the stimulation-producing target action, but also actions similar to the target action and actions that occurred a few seconds before stimulation, and repeated pairings led to a gradual refinement of the behavioural repertoire to home in on the target actions.

  • Jonathan C. Y. Tang
  • , Vitor Paixao
  •  & Rui M. Costa

• Article | 05 April 2023

  Plastic and stimulus-specific coding of salient events in the central amygdala

  Neurons in the central amygdala contribute to the reward prediction error responses of dopamine neurons to facilitate reward learning, but are not involved in aversive learning.

  • Tao Yang
  • , Kai Yu
  •  & Bo Li

• Article | 01 June 2022

  Spatiotemporal dynamics of noradrenaline during learned behaviour

  Noradrenaline-expressing neurons in the locus coeruleus in mouse facilitate task execution and encode reinforcement in learning tasks, via partially modular projections to the cortex.

  • Vincent Breton-Provencher
  • , Gabrielle T. Drummond
  •  & Mriganka Sur

• Article
  21 April 2021 | Open Access

  Mouse prefrontal cortex represents learned rules for categorization

  Neurons in the mouse medial prefrontal cortex acquire category-selective responses with learning.

  • Sandra Reinert
  • , Mark Hübener
  •  & Pieter M. Goltstein

• Article | 24 February 2021

  Reset of hippocampal–prefrontal circuitry facilitates learning

  Exposure to a novel experience can ‘reset’ connections between the hippocampus and prefrontal cortex in mice, allowing them to overcome an existing learned behaviour and to replace it with a new one.

  • Alan J. Park
  • , Alexander Z. Harris
  •  & Joshua A. Gordon

• Article | 23 December 2020

  Cell-type-specific asynchronous modulation of PKA by dopamine in learning

  The net PKA activities in each class of spiny projection neuron in the nucleus accumbens of the mouse are dichotomously modulated by asynchronous positive and negative dopamine signals during different phases of learning.

  • Suk Joon Lee
  • , Bart Lodder
  •  & Bernardo L. Sabatini

• Article | 22 May 2019

  Dissociable dopamine dynamics for learning and motivation

  The dopamine projection from midbrain dopamine cells to the nucleus accumbens is essential for normal motivation, yet motivation-related changes in nucleus accumbens dopamine release occur independently of dopamine cell firing.

  • Ali Mohebi
  • , Jeffrey R. Pettibone
  •  & Joshua D. Berke