Molecular Diagnostics
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Open Access
Featured
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Molecular Diagnostics
| Open AccessNovel immunohistochemistry-based signatures to predict metastatic site of triple-negative breast cancers
- Sergey Klimov
- , Padmashree CG Rida
- & Ritu Aneja
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Molecular Diagnostics
| Open AccessThe TGF-β signalling negative regulator PICK1 represses prostate cancer metastasis to bone
- Yuhu Dai
- , Dong Ren
- & Xinsheng Peng
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Mini Review
| Open AccessMitochondria on the move: emerging paradigms of organelle trafficking in tumour plasticity and metastasis
- Dario C Altieri
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Molecular Diagnostics
| Open AccessMiR-646 inhibited cell proliferation and EMT-induced metastasis by targeting FOXK1 in gastric cancer
- P Zhang
- , W M Tang
- & J D Wang
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Molecular Diagnostics
| Open AccessTargeting of CCBE1 by miR-330-3p in human breast cancer promotes metastasis
- Aruz Mesci
- , Xiaoyong Huang
- & Stanley K Liu
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Molecular Diagnostics
| Open AccessTumour-derived alkaline phosphatase regulates tumour growth, epithelial plasticity and disease-free survival in metastatic prostate cancer
- S R Rao
- , A E Snaith
- & C M Edwards
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Molecular Diagnostics
| Open AccessExpression profiling of budding cells in colorectal cancer reveals an EMT-like phenotype and molecular subtype switching
- Linde De Smedt
- , Sofie Palmans
- & Xavier Sagaert
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Molecular Diagnostics
| Open AccessThe FOXD3/miR-214/MED19 axis suppresses tumour growth and metastasis in human colorectal cancer
- G Y He
- , J L Hu
- & L Liang
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Short Communication
| Open AccessIncorporating multiparametric MRI staging and the new histological Grade Group system improves risk-stratified detection of bone metastasis in prostate cancer
- David Thurtle
- , Ray C J Hsu
- & Tristan Barrett
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Clinical Study
| Open AccessRADVAN: a randomised phase 2 trial of WBRT plus vandetanib for melanoma brain metastases – results and lessons learnt
- Avinash Gupta
- , Corran Roberts
- & Mark R Middleton
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Clinical Study
| Open AccessAxillary lymph node micrometastases decrease triple-negative early breast cancer survival
- G Houvenaeghel
- , R Sabatier
- & E Lambaudie
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Molecular Diagnostics
| Open AccessDetection of micrometastases by flow cytometry in sentinel lymph nodes from patients with renal tumours
- Ciputra Adijaya Hartana
- , Johan Kinn
- & Ola Winqvist
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Review
| Open AccessTransforming growth factor β as regulator of cancer stemness and metastasis
- Claudia Bellomo
- , Laia Caja
- & Aristidis Moustakas
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Clinical Study
| Open AccessPatterns of progression, treatment of progressive disease and post-progression survival in the New EPOC study
- Siân A Pugh
- , Megan Bowers
- & John N Primrose
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Molecular Diagnostics
| Open AccessCancer cell-derived 12(S)-HETE signals via 12-HETE receptor, RHO, ROCK and MLC2 to induce lymph endothelial barrier breaching
- Chi Huu Nguyen
- , Serena Stadler
- & Georg Krupitza
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Molecular Diagnostics
| Open AccessKI67 and DLX2 predict increased risk of metastasis formation in prostate cancer–a targeted molecular approach
- William JF Green
- , Graham Ball
- & Desmond G Powe
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Molecular Diagnostics
| Open AccessSpecific KRAS amino acid substitutions and EGFR mutations predict site-specific recurrence and metastasis following non-small-cell lung cancer surgery
- Stéphane Renaud
- , Joseph Seitlinger
- & Gilbert Massard
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Clinical Study
| Open AccessThe impact of hepatic fibrosis on the incidence of liver metastasis from colorectal cancer
- Takayuki Kondo
- , Koji Okabayashi
- & Yuko Kitagawa
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Translational Therapeutics
| Open AccessCCR6 expression in colon cancer is associated with advanced disease and supports epithelial-to-mesenchymal transition
- Neeraj Kapur
- , Hina Mir
- & Shailesh Singh
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Clinical Study
| Open AccessFirst-in-human phase I study of the DNA-repair inhibitor DT01 in combination with radiotherapy in patients with skin metastases from melanoma
- C Le Tourneau
- , B Dreno
- & M Dutreix
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Translational Therapeutics
| Open AccessMetastasis-inducing proteins are widely expressed in human brain metastases and associated with intracranial progression and radiation response
- Rasheed Zakaria
- , Angela Platt-Higgins
- & Philip S Rudland
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Molecular Diagnostics
| Open AccessThe presence of intraepithelial CD45RO+ cells in resected lymph nodes with metastases from NSCLC patients is an independent predictor of disease-specific survival
- Thomas K Kilvaer
- , Erna-Elise Paulsen
- & Tom Donnem
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Clinical Study
| Open AccessEvaluation of Angiopoietin-2 as a biomarker in gastric cancer: results from the randomised phase III AVAGAST trial
- Ulrich T Hacker
- , Laura Escalona-Espinosa
- & Hildegard Büning
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Translational Therapeutics
| Open AccessAcute changes in liver tumour perfusion measured non-invasively with arterial spin labelling
- S Peter Johnson
- , Rajiv Ramasawmy
- & Simon Walker-Samuel
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Molecular Diagnostics
| Open AccessCadherin-5: a biomarker for metastatic breast cancer with optimum efficacy in oestrogen receptor-positive breast cancers with vascular invasion
- Simon A Fry
- , Claire E Robertson
- & Miriam V Dwek
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Translational Therapeutics
| Open AccessHexokinase 2 is a determinant of neuroblastoma metastasis
- Liat Edry Botzer
- , Shelly Maman
- & Isaac P Witz
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Molecular Diagnostics
| Open AccessChanging molecular profile of brain metastases compared with matched breast primary cancers and impact on clinical outcomes
- A H Thomson
- , J McGrane
- & R Jenkins
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Molecular Diagnostics
| Open AccessE-Cadherin fragments as potential mediators for peritoneal metastasis in advanced epithelial ovarian cancer
- Fabian Trillsch
- , Sascha Kuerti
- & Sven Mahner
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Clinical Study
| Open AccessBone marrow micrometastases in early breast cancer–30-year outcome
- J Mansi
- , J Morden
- & R C Coombes
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Translational Therapeutics
| Open AccessLoss of CDH1 (E-cadherin) expression is associated with infiltrative tumour growth and lymph node metastasis
- Sun A Kim
- , Kentaro Inamura
- & Zhi Rong Qian
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Molecular Diagnostics
| Open AccessPrediction of vascular invasion in hepatocellular carcinoma by next-generation des-r-carboxy prothrombin
- Tomoharu Kurokawa
- , Shintaro Yamazaki
- & Tadatoshi Takayama
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Molecular Diagnostics
| Open AccessMelanoma-expressed CD70 is involved in invasion and metastasis
- Christine Pich
- , Guillaume Sarrabayrouse
- & Anne-Françoise Tilkin-Mariamé
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Molecular Diagnostics
| Open AccessMYB is a novel regulator of pancreatic tumour growth and metastasis
- Sanjeev K Srivastava
- , Arun Bhardwaj
- & Ajay P Singh
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Clinical Study
| Open AccessA randomised, double-blind, placebo-controlled multi-centre phase III trial of XELIRI/FOLFIRI plus simvastatin for patients with metastatic colorectal cancer
- S H Lim
- , T W Kim
- & W K Kang
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Translational Therapeutics
| Open AccessPathological responses after angiogenesis or EGFR inhibitors in metastatic colorectal cancer depend on the chemotherapy backbone
- J Carrasco
- , M Gizzi
- & M Van den Eynde
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Molecular Diagnostics
| Open AccessLoss of FOXO1 promotes gastric tumour growth and metastasis through upregulation of human epidermal growth factor receptor 2/neu expression
- Young San Ko
- , Sung Jin Cho
- & Byung Lan Lee
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Clinical Study
| Open AccessClinical nomogram to predict bone-only metastasis in patients with early breast carcinoma
- Yann Delpech
- , Sami I Bashour
- & Nuhad K Ibrahim
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Clinical Study
| Open AccessUpfront FOLFOXIRI+bevacizumab followed by fluoropyrimidin and bevacizumab maintenance in patients with molecularly unselected metastatic colorectal cancer
- Alexander Stein
- , Djordje Atanackovic
- & Carsten Bokemeyer
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Clinical Study
| Open AccessBrain metastases in gastro-oesophageal adenocarcinoma: insights into the role of the human epidermal growth factor receptor 2 (HER2)
- J Feilchenfeldt
- , Z Varga
- & S Hofer
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Molecular Diagnostics
| Open AccessWISP-2 in human gastric cancer and its potential metastatic suppressor role in gastric cancer cells mediated by JNK and PLC-γ pathways
- Jiafu Ji
- , Shuqin Jia
- & Wen G Jiang
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Translational Therapeutics
| Open AccessMacrophage subtype predicts lymph node metastasis in oesophageal adenocarcinoma and promotes cancer cell invasion in vitro
- Wenqing Cao
- , Jeffrey H Peters
- & JiangZhou Yu
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Molecular Diagnostics
| Open AccessMDA-MB-231 breast cancer cells overexpressing single VEGF isoforms display distinct colonisation characteristics
- Melanie Di Benedetto
- , Aurore Toullec
- & Martine Perrot-Applanat
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Molecular Diagnostics
| Open AccessOverexpression of connexin 43 reduces melanoma proliferative and metastatic capacity
- A Tittarelli
- , I Guerrero
- & F Salazar-Onfray
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Molecular Diagnostics
| Open AccessAssociation between cytosolic expression of BRCA1 and metastatic risk in breast cancer
- W L Santivasi
- , H Wang
- & Fen Xia
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Molecular Diagnostics
| Open AccessOncogenic CXCL10 signalling drives metastasis development and poor clinical outcome
- S C Wightman
- , A Uppal
- & N N Khodarev
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Full Paper
| Open AccessRevisiting the transcriptional analysis of primary tumours and associated nodal metastases with enhanced biological and statistical controls: application to thyroid cancer
- M Tarabichi
- , M Saiselet
- & V Detours
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Clinical Study
| Open Access18F-fluorodeoxyglucose positron-emission tomography-computed tomography to diagnose recurrent cancer
- J J You
- , K J Cline
- & M N Levine
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Full Paper
| Open AccessDNA ploidy in curettage specimens identifies high-risk patients and lymph node metastasis in endometrial cancer
- T S Njølstad
- , J Trovik
- & H E Danielsen
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Molecular Diagnostics
| Open AccessHairy/enhancer-of-split related with YRPW motif protein 1 promotes osteosarcoma metastasis via matrix metallopeptidase 9 expression
- A Tsuru
- , T Setoguchi
- & S Komiya