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| Open AccessHSF-1/miR-145-5p transcriptional axis enhances hyperthermic intraperitoneal chemotherapy efficacy on peritoneal ovarian carcinosis
- Silvia Di Agostino
- , Valeria Canu
- & Giovanni Blandino
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Article
| Open Accessp53 isoform expression promotes a stemness phenotype and inhibits doxorubicin sensitivity in breast cancer
- Luiza Steffens Reinhardt
- , Kira Groen
- & Kelly A. Avery-Kiejda
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Article
| Open AccessHistone acetylation by HBO1 (KAT7) activates Wnt/β-catenin signaling to promote leukemogenesis in B-cell acute lymphoblastic leukemia
- Hao Wang
- , Yingqi Qiu
- & Yuhua Li
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Article
| Open AccessFDW028, a novel FUT8 inhibitor, impels lysosomal proteolysis of B7-H3 via chaperone-mediated autophagy pathway and exhibits potent efficacy against metastatic colorectal cancer
- Mengmeng Wang
- , Zhoudong Zhang
- & Weipeng Wang
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Article
| Open AccessInhibition of autotaxin alleviates pathological features of hepatic encephalopathy at the level of gut–liver–brain axis: an experimental and bioinformatic study
- Ali Sepehrinezhad
- , Ali Shahbazi
- & Sajad Sahab Negah
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Article
| Open AccessDEF6(differentially exprehomolog) exacerbates pathological cardiac hypertrophy via RAC1
- Yan Sun
- , Changlu Xu
- & Xi Jiang
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Article
| Open AccessLoss of TP53 cooperates with c-MET overexpression to drive hepatocarcinogenesis
- Yi Zhou
- , Guofei Cui
- & Haichuan Wang
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Article
| Open AccessJUN-induced super-enhancer RNA forms R-loop to promote nasopharyngeal carcinoma metastasis
- Qunying Jia
- , Yuan Tan
- & Faqin Tang
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Article
| Open AccessSPRR1A is a key downstream effector of MiR-150 during both maladaptive cardiac remodeling in mice and human cardiac fibroblast activation
- Satoshi Kawaguchi
- , Bruno Moukette
- & Il-man Kim
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Article
| Open AccessTolerance of repeated toxic injuries of murine livers is associated with steatosis and inflammation
- Seddik Hammad
- , Christoph Ogris
- & Nikola S. Mueller
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Article
| Open AccessA novel CTLA-4 blocking strategy based on nanobody enhances the activity of dendritic cell vaccine-stimulated antitumor cytotoxic T lymphocytes
- Wenli Yang
- , Yanyang Pang
- & Wu Wang
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Article
| Open AccessInhibition of TRPV4 remodels single cell polarity and suppresses the metastasis of hepatocellular carcinoma
- Jian Liu
- , Yongjian Guo
- & Libin Wei
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Article
| Open AccessHNF4A-BAP31-VDAC1 axis synchronously regulates cell proliferation and ferroptosis in gastric cancer
- Qingqing Zhou
- , Tengfei Liu
- & Jun Zhang
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Article
| Open AccessMETTL3-dependent m6A methylation facilitates uterine receptivity and female fertility via balancing estrogen and progesterone signaling
- Shuo Wan
- , Yadong Sun
- & Meixiang Yang
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Article
| Open AccessActivation of HIF-1α C-terminal transactivation domain protects against hypoxia-induced kidney injury through hexokinase 2-mediated mitophagy
- Zuo-Lin Li
- , Lin Ding
- & Bi-Cheng Liu
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Article
| Open AccessWhey-based diet containing medium chain triglycerides modulates the gut microbiota and protects the intestinal mucosa from chemotherapy while maintaining therapy efficacy
- Hannah R. Wardill
- , Ana Rita Da Silva Ferreira
- & Wim J. E. Tissing
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Review Article
| Open AccessNitroglycerin: a comprehensive review in cancer therapy
- Mélina Meunier
- , Aline Yammine
- & Stéphanie Plenchette
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Article
| Open AccessClinical-grade human umbilical cord-derived mesenchymal stem cells improved skeletal muscle dysfunction in age-associated sarcopenia mice
- Chao Wang
- , Bichun Zhao
- & Wen Yue
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Article
| Open AccessInterferon-gamma is quintessential for NOS2 and COX2 expression in ER- breast tumors that lead to poor outcome
- Robert Y. S. Cheng
- , Lisa A. Ridnour
- & David A. Wink
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Article
| Open AccessInhibition of extranodal NK/T-cell lymphoma by Chiauranib through an AIF-dependent pathway and its synergy with L-asparaginase
- Tianxiao Gao
- , Jieye Huang
- & Zhiming Li
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Article
| Open AccessRadiation therapy improves CAR T cell activity in acute lymphoblastic leukemia
- Mayumi Sugita
- , Takahiro Yamazaki
- & Monica L. Guzman
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Article
| Open AccessCHRM4/AKT/MYCN upregulates interferon alpha-17 in the tumor microenvironment to promote neuroendocrine differentiation of prostate cancer
- Yu-Ching Wen
- , Van Thi Ngoc Tram
- & Yen-Nien Liu
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Article
| Open AccessTherapeutic efficacy of a MMAE-based anti-DR5 drug conjugate Oba01 in preclinical models of pancreatic cancer
- Chao Zheng
- , Dongdong Zhou
- & Shuyong Zhang
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Article
| Open AccessPost-transcriptional modification of m6A methylase METTL3 regulates ERK-induced androgen-deprived treatment resistance prostate cancer
- Yang Li
- , Shimiao Zhu
- & Zhiqun Shang
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Article
| Open AccessPRR15 deficiency facilitates malignant progression by mediating PI3K/Akt signaling and predicts clinical prognosis in triple-negative rather than non-triple-negative breast cancer
- Fengzhu Guo
- , Jialu Ma
- & Binghe Xu
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Article
| Open AccessEnhancer of zeste homolog 2 promotes renal fibrosis after acute kidney injury by inducing epithelial-mesenchymal transition and activation of M2 macrophage polarization
- Xun Zhou
- , Hui Chen
- & Na Liu
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Meeting Report
| Open Access10th International Multithematic Scientific Bio-Medical Congress (IMBMC), Nicosia, Cyprus, 2022
- Panayiota Christodoulou
- , Maria-Areti Salamouri
- & Ioannis Patrikios
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Article
| Open AccessMitochondria-derived H2O2 triggers liver regeneration via FoxO3a signaling pathway after partial hepatectomy in mice
- Hua Bai
- , Cong-Wen Fang
- & Xu-Jun Qin
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Article
| Open AccessHOXB3 drives WNT-activation associated progression in castration-resistant prostate cancer
- Shimiao Zhu
- , Zhao Yang
- & Yuanjie Niu
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Article
| Open AccessHIF1α-BNIP3-mediated mitophagy protects against renal fibrosis by decreasing ROS and inhibiting activation of the NLRP3 inflammasome
- Jialin Li
- , Qisheng Lin
- & Zhaohui Ni
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Article
| Open AccessSupplementation with α-ketoglutarate improved the efficacy of anti-PD1 melanoma treatment through epigenetic modulation of PD-L1
- Nian Liu
- , Jianglin Zhang
- & Cong Peng
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Article
| Open AccessLong non-coding RNA DLX6-AS1 is the key mediator of glomerular podocyte injury and albuminuria in diabetic nephropathy by targeting the miR-346/GSK-3β signaling pathway
- Jia Guo
- , Wen Zheng
- & Zhangsuo Liu
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Article
| Open AccessDAPL1 prevents epithelial–mesenchymal transition in the retinal pigment epithelium and experimental proliferative vitreoretinopathy
- Xiaoyin Ma
- , Shuxian Han
- & Ling Hou
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Article
| Open AccessRETRACTED ARTICLE: Ibrutinib facilitates the sensitivity of colorectal cancer cells to ferroptosis through BTK/NRF2 pathway
- Jin-Feng Zhu
- , Yi Liu
- & Wei Zeng
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Review Article
| Open AccessGlutathione system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis
- Mingyue Tan
- , Yunfei Yin
- & Hongxia Li
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Article
| Open AccessTPX2 enhances the transcription factor activation of PXR and enhances the resistance of hepatocellular carcinoma cells to antitumor drugs
- Hongbo Wang
- , Fang Chu
- & Bo-an Li
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Article
| Open AccessLongitudinal efficacy and toxicity of SARS-CoV-2 vaccination in cancer patients treated with immunotherapy
- Pavlina Spiliopoulou
- , Helena J. Janse van Rensburg
- & Lillian L. Siu
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Article
| Open AccessImpact of AMPK on cervical carcinoma progression and metastasis
- Paweł Konieczny
- , Tomasz Adamus
- & Marcin Majka
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Article
| Open AccessSingle-cell RNA-seq integrated with multi-omics reveals SERPINE2 as a target for metastasis in advanced renal cell carcinoma
- Wen-jin Chen
- , Ke-qin Dong
- & Xin-gang Cui
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Article
| Open AccessTRAF6 regulates the abundance of RIPK1 and inhibits the RIPK1/RIPK3/MLKL necroptosis signaling pathway and affects the progression of colorectal cancer
- Penghang Lin
- , Chunlin Lin
- & Guangwei Zhu
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Article
| Open AccessResveratrol rescues cutaneous radiation-induced DNA damage via a novel AMPK/SIRT7/HMGB1 regulatory axis
- Yi Jin
- , Xingyuan Liu
- & Liang Zhou
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Article
| Open AccessTumor immune microenvironment and immunotherapy efficacy in BRAF mutation non-small-cell lung cancer
- Hui Li
- , Yongchang Zhang
- & Yun Fan
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Article
| Open AccessDC vaccines loaded with glioma cells killed by photodynamic therapy induce Th17 anti-tumor immunity and provide a four-gene signature for glioma prognosis
- Maria Vedunova
- , Victoria Turubanova
- & Dmitri V. Krysko
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Article
| Open AccessTubular β-catenin alleviates mitochondrial dysfunction and cell death in acute kidney injury
- Hongyu Li
- , Joseph C. K. Leung
- & Sydney C. W. Tang
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Article
| Open AccessGlucocorticoid-induced microRNA-378 signaling mediates the progression of pancreatic cancer by enhancing autophagy
- Li Liu
- , Shanshan Han
- & Ingrid Herr
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Article
| Open AccessEmbryonic organizer formation disorder leads to multiorgan dysplasia in Down syndrome
- Yanyan Liu
- , Ziyuan Lin
- & Huaqin Sun
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Article
| Open AccessTRPM8 contributes to liver regeneration via mitochondrial energy metabolism mediated by PGC1α
- Xiaohua Lei
- , Qiang Liu
- & Xundi Xu
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Article
| Open AccessMatrix protein Tenascin-C promotes kidney fibrosis via STAT3 activation in response to tubular injury
- Qionghong Xie
- , Min Zhang
- & Chuan-Ming Hao
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Article
| Open AccessIdarubicin combats abiraterone and enzalutamide resistance in prostate cells via targeting XPA protein
- Ying Zhang
- , Wei Wei
- & Changlin Li