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| Open AccessVentricular Netrin-1 deficiency leads to defective pyramidal decussation and mirror movement in mice
- Ling Hu
- , Xi-Yue Liu
- & Yu-Qiang Ding
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Article
| Open AccessHAP40 modulates mutant Huntingtin aggregation and toxicity in Huntington’s disease mice
- Laiqiang Chen
- , Yiyang Qin
- & Su Yang
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Article
| Open AccessPirh2 modulates the mitochondrial function and cytochrome c-mediated neuronal death during Alzheimer’s disease
- Abhishek Singh
- , Shubhangini Tiwari
- & Sarika Singh
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Article
| Open AccessActin-nucleation promoting factor N-WASP influences alpha-synuclein condensates and pathology
- Joshua Jackson
- , Christian Hoffmann
- & Daniele Bano
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Article
| Open AccessProtective effect of increased O-GlcNAc cycling against 6-OHDA induced Parkinson’s disease pathology
- Dong Yeol Kim
- , Sang-Min Kim
- & Inn-Oc Han
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Article
| Open AccessmiR-277 targets the proapoptotic gene-hid to ameliorate Aβ42-mediated neurodegeneration in Alzheimer’s model
- Prajakta Deshpande
- , Chao-Yi Chen
- & Amit Singh
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Article
| Open AccessScreens in aging-relevant human ALS-motor neurons identify MAP4Ks as therapeutic targets for the disease
- Meng-Lu Liu
- , Shuaipeng Ma
- & Chun-Li Zhang
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Article
| Open AccessLocal production of reactive oxygen species drives vincristine-induced axon degeneration
- Jorge Gomez-Deza
- , Anastasia L. Slavutsky
- & Claire E. Le Pichon
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Article
| Open AccessMitochondria dysregulation contributes to secondary neurodegeneration progression post-contusion injury in human 3D in vitro triculture brain tissue model
- Volha Liaudanskaya
- , Nicholas J. Fiore
- & David L. Kaplan
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Article
| Open AccessN-Acetyltransferase 9 ameliorates Aβ42-mediated neurodegeneration in the Drosophila eye
- Prajakta Deshpande
- , Anuradha Venkatakrishnan Chimata
- & Amit Singh
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Article
| Open AccessStatins suppress cell-to-cell propagation of α-synuclein by lowering cholesterol
- Joo-Ok Min
- , Hoang-Anh Ho
- & Seung-Jae Lee
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Article
| Open AccessKlotho prevents transforming growth factor-β2-induced senescent-like morphological changes in the retinal pigment epithelium
- Ha Young Jang
- , Soo-Jin Kim
- & Jeong Hun Kim
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Article
| Open AccessMultiple sclerosis plasma IgG aggregates induce complement-dependent neuronal apoptosis
- Wenbo Zhou
- , Michael Graner
- & Xiaoli Yu
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Article
| Open AccessSphingomyelin 16:0 is a therapeutic target for neuronal death in acid sphingomyelinase deficiency
- Ángel Gaudioso
- , Xuntian Jiang
- & María Dolores Ledesma
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Article
| Open AccessBlocking dPerk in the intestine suppresses neurodegeneration in a Drosophila model of Parkinson’s disease
- Rebeka Popovic
- , Amrita Mukherjee
- & L. Miguel Martins
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Article
| Open AccessCdh5-mediated Fpn1 deletion exerts neuroprotective effects during the acute phase and inhibitory effects during the recovery phase of ischemic stroke
- Huiwen Zheng
- , Xin Guo
- & Yan-zhong Chang
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Article
| Open AccessAugmenting hematoma-scavenging capacity of innate immune cells by CDNF reduces brain injury and promotes functional recovery after intracerebral hemorrhage
- Kuan-Yin Tseng
- , Vassilis Stratoulias
- & Hock-Kean Liew
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Review Article
| Open AccessPyroptosis and degenerative diseases of the elderly
- Jiamin Zhou
- , Jingjing Qiu
- & Yan Sun
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Article
| Open AccessMicroglia and meningeal macrophages depletion delays the onset of experimental autoimmune encephalomyelitis
- Alejandro Montilla
- , Alazne Zabala
- & María Domercq
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Article
| Open AccessThe length of uninterrupted CAG repeats in stem regions of repeat disease associated hairpins determines the amount of short CAG oligonucleotides that are toxic to cells through RNA interference
- Andrea E. Murmann
- , Monal Patel
- & Marcus E. Peter
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Article
| Open AccessAstrocyte-derived exosomal nicotinamide phosphoribosyltransferase (Nampt) ameliorates ischemic stroke injury by targeting AMPK/mTOR signaling to induce autophagy
- Yang Deng
- , Rui Duan
- & Junrong Zhu
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Article
| Open AccessNeuronal haemoglobin induces loss of dopaminergic neurons in mouse Substantia nigra, cognitive deficits and cleavage of endogenous α-synuclein
- Chiara Santulli
- , Carlotta Bon
- & Stefano Gustincich
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Article
| Open AccessMuscular Swedish mutant APP-to-Brain axis in the development of Alzheimer’s disease
- Jin-Xiu Pan
- , Daehoon Lee
- & Wen-Cheng Xiong
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Article
| Open AccessGlioblastoma cell motility depends on enhanced oxidative stress coupled with mobilization of a sulfurtransferase
- Mirca S. Saurty-Seerunghen
- , Thomas Daubon
- & Marie-Pierre Junier
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Article
| Open AccessModeling native and seeded Synuclein aggregation and related cellular dysfunctions in dopaminergic neurons derived by a new set of isogenic iPSC lines with SNCA multiplications
- Angelo Iannielli
- , Mirko Luoni
- & Vania Broccoli
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Article
| Open AccessProtein synthesis inhibition and loss of homeostatic functions in astrocytes from an Alzheimer’s disease mouse model: a role for ER-mitochondria interaction
- Laura Tapella
- , Giulia Dematteis
- & Dmitry Lim
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Article
| Open AccessCaspase-1 inhibition improves cognition without significantly altering amyloid and inflammation in aged Alzheimer disease mice
- Joseph Flores
- , Marie-Lyne Fillion
- & Andréa C. LeBlanc
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Article
| Open AccessFMRP modulates the Wnt signalling pathway in glioblastoma
- Giorgia Pedini
- , Mariachiara Buccarelli
- & Claudia Bagni
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Article
| Open AccessSARM1 deletion in parvalbumin neurons is associated with autism-like behaviors in mice
- Ludan Xiang
- , Qian Wu
- & Zhihui Huang
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Article
| Open AccessTranscription factor EB-mediated mesenchymal stem cell therapy induces autophagy and alleviates spinocerebellar ataxia type 3 defects in neuronal cells model
- Xiaobo Han
- , Jean de Dieu Habimana
- & Zhiyuan Li
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Article
| Open AccessMid1 is associated with androgen-dependent axonal vulnerability of motor neurons in spinal and bulbar muscular atrophy
- Yosuke Ogura
- , Kentaro Sahashi
- & Masahisa Katsuno
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Article
| Open Accesscirc-Pank1 promotes dopaminergic neuron neurodegeneration through modulating miR-7a-5p/α-syn pathway in Parkinson’s disease
- Qing Liu
- , Qiyao Li
- & Lei Wang
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Article
| Open AccessRestoration of ER proteostasis attenuates remote apoptotic cell death after spinal cord injury by reducing autophagosome overload
- Elisa Bisicchia
- , Roberta Mastrantonio
- & Maria Teresa Viscomi
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Article
| Open AccessInsulin receptor activation by proinsulin preserves synapses and vision in retinitis pigmentosa
- Alonso Sánchez-Cruz
- , Alberto Hernández-Pinto
- & Enrique J. de la Rosa
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Article
| Open AccessInhibition of the CEBPβ-NFκB interaction by nanocarrier-packaged Carnosic acid ameliorates glia-mediated neuroinflammation and improves cognitive function in an Alzheimer’s disease model
- Wang Yi-Bin
- , Li Xiang
- & Wang Chun-Yan
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Article
| Open AccessDeficiency of N-glycanase 1 perturbs neurogenesis and cerebral development modeled by human organoids
- Victor J. T. Lin
- , Jiangnan Hu
- & Yu-Chieh Wang
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Article
| Open AccessMassive iron accumulation in PKAN-derived neurons and astrocytes: light on the human pathological phenotype
- Paolo Santambrogio
- , Maddalena Ripamonti
- & Sonia Levi
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Article
| Open AccessPINK1-parkin-mediated neuronal mitophagy deficiency in prion disease
- Jie Li
- , Mengyu Lai
- & Lifeng Yang
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Article
| Open AccessRab35 and glucocorticoids regulate APP and BACE1 trafficking to modulate Aβ production
- Viktoriya Zhuravleva
- , João Vaz-Silva
- & Clarissa L. Waites
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Article
| Open AccessOligodendrocytes depend on MCL-1 to prevent spontaneous apoptosis and white matter degeneration
- Abigail H. Cleveland
- , Alejandra Romero-Morales
- & Timothy R. Gershon
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Article
| Open AccessEnriched environment and visual stimuli protect the retinal pigment epithelium and photoreceptors in a mouse model of non-exudative age-related macular degeneration
- Hernán H. Dieguez
- , Juan S. Calanni
- & Damián Dorfman
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Article
| Open AccessAutophagy in Spinocerebellar ataxia type 2, a dysregulated pathway, and a target for therapy
- Adriana Marcelo
- , Inês T. Afonso
- & Clévio Nóbrega
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Article
| Open AccessThe brain targeted delivery of programmed cell death 4 specific siRNA protects mice from CRS-induced depressive behavior
- Yufeng Jia
- , Xiao Zhuang
- & Lining Zhang
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Article
| Open AccessA missense mutation in Pitx2 leads to early-onset glaucoma via NRF2-YAP1 axis
- Yeming Yang
- , Xiao Li
- & Xianjun Zhu
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Article
| Open AccessCHD8 safeguards early neuroectoderm differentiation in human ESCs and protects from apoptosis during neurogenesis
- Song Ding
- , Xianchun Lan
- & Wei Jiang
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Article
| Open AccessHippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer’s disease
- Jens V. Andersen
- , Niels H. Skotte
- & Helle S. Waagepetersen
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Article
| Open AccessTargeting the miRNA-155/TNFSF10 network restrains inflammatory response in the retina in a mouse model of Alzheimer’s disease
- Chiara Burgaletto
- , Chiara Bianca Maria Platania
- & Giuseppina Cantarella
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Article
| Open AccessAstrocytic YAP prevents the demyelination through promoting expression of cholesterol synthesis genes in experimental autoimmune encephalomyelitis
- Jingjing Zhang
- , Xingxing Xu
- & Zhihui Huang
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Article
| Open AccessAlpha-Synuclein defects autophagy by impairing SNAP29-mediated autophagosome-lysosome fusion
- Qilin Tang
- , Pan Gao
- & Thomas Koeglsperger
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