Article
|
Open Access
Featured
-
-
Article |
Plastic and stimulus-specific coding of salient events in the central amygdala
Neurons in the central amygdala contribute to the reward prediction error responses of dopamine neurons to facilitate reward learning, but are not involved in aversive learning.
- Tao Yang
- , Kai Yu
- & Bo Li
-
Article
| Open Access
Mesolimbic dopamine adapts the rate of learning from action
Analysis of data collected from mice learning a trace conditioning paradigm shows that phasic dopamine activity in the brain can regulate direct learning of behavioural policies, and dopamine sets an adaptive learning rate rather than an error-like teaching signal.
- Luke T. Coddington
- , Sarah E. Lindo
- & Joshua T. Dudman
-
Article |
Differential mechanisms underlie trace and delay conditioning in Drosophila
Trace and delay conditioning experiments in Drosophila reveal the different neurons and signalling mechanisms that underlie this behaviour and highlight similarities with observations of learning experiences in mammals.
- Dhruv Grover
- , Jen-Yung Chen
- & Ralph J. Greenspan
-
Article |
Intercalated amygdala clusters orchestrate a switch in fear state
Distinct clusters of inhibitory neurons in the mouse amygdala perform opposing roles in fear extinction.
- Kenta M. Hagihara
- , Olena Bukalo
- & Andrew Holmes
-
Article |
Amygdala inhibitory neurons as loci for translation in emotional memories
Protein synthesis is required in distinct populations of inhibitory neurons in the mouse amygdala to store memories of danger and safety.
- Prerana Shrestha
- , Zhe Shan
- & Eric Klann
-
Article |
Dopamine D2 receptors in discrimination learning and spine enlargement
Detection of dopamine dips by neurons that express dopamine D2 receptors in the striatum is used to refine generalized reward conditioning mediated by dopamine D1 receptors.
- Yusuke Iino
- , Takeshi Sawada
- & Sho Yagishita
-
Letter |
Sensory experience remodels genome architecture in neural circuit to drive motor learning
The authors identify a role for genome architecture reorganization in anterior dorsal cerebellar vermis granule neurons in learning a conditioned startle paradigm in mice.
- Tomoko Yamada
- , Yue Yang
- & Azad Bonni
-
Letter |
Re-evaluation of learned information in Drosophila
Depending on prediction accuracy at the time of memory recall, specific mushroom body output neurons drive different combinations of dopaminergic neurons to extinguish or reconsolidate appetitive memory in Drosophila.
- Johannes Felsenberg
- , Oliver Barnstedt
- & Scott Waddell
-
Article |
Neural ensemble dynamics underlying a long-term associative memory
Use of a head-mounted miniature microscope in awake, behaving mice reveals that neural ensembles in the basal and lateral amygdala encode associations between conditioned and unconditioned stimuli in a way that matches models of supervised learning.
- Benjamin F. Grewe
- , Jan Gründemann
- & Mark J. Schnitzer
-
Article |
Glia-derived neurons are required for sex-specific learning in C. elegans
In the worm C. elegans, a previously unidentified pair of bilateral neurons in the male (termed MCMs) are shown to arise from differentiated glial cells upon sexual maturation; these neurons are essential for a male-specific form of associative learning which balances chemotactic responses with reproductive priorities.
- Michele Sammut
- , Steven J. Cook
- & Arantza Barrios
-
Letter |
A circuit mechanism for differentiating positive and negative associations
Neurons in the basolateral amygdala projecting to canonical fear or reward circuits undergo opposing changes in synaptic strength following fear or reward conditioning, and selectively activating these projection-target-defined neural populations causes either negative or positive reinforcement, respectively.
- Praneeth Namburi
- , Anna Beyeler
- & Kay M. Tye
-
Letter |
A single pair of interneurons commands the Drosophila feeding motor program
A pair of Drosophila brain cells is identified and its activation alone is found to induce the fly’s complete feeding motor routine when artificially induced; suppressing or ablating these two neurons eliminates the sugar-induced feeding behaviour, but ablation of just one neuron results in asymmetric movements.
- Thomas F. Flood
- , Shinya Iguchi
- & Motojiro Yoshihara
-
News |
How to learn in your sleep
New information can be learned while asleep, and retained after waking.
- Mo Costandi
Multisensory learning binds neurons into a cross-modal memory engram