Featured
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News & Views |
A ‘Swiss army knife’ probe for metastatic cancers
A nanosensor probe that combines a tumour-targeting peptide, a diagnostic reporter and an imaging contrast agent enables early diagnosis, precision imaging, disease stratification and downstream therapeutic response monitoring of metastatic cancer.
- Matthew Bogyo
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News & Views |
Learning with brain chemistry
Organic neuromorphic devices are now able to take direct input from cellular neurotransmitter release.
- Tobias Cramer
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Article |
Tracking intracellular forces and mechanical property changes in mouse one-cell embryo development
Mechanical properties and forces sculpt the behaviour of cells in living organisms. Silicon-based nanochips implanted into mouse one-cell embryos have been used to reveal mechanical changes during the early onset of embryonic development.
- Marta Duch
- , Núria Torras
- & Anthony C. F. Perry
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News & Views |
Gas vesicles as collapsible MRI contrast agents
Microbial gas vesicles have been developed for use as MRI contrast agents whose contrast can be inactivated by applying ultrasound waves to collapse the vesicles.
- Jeff W. M. Bulte
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Article |
Acoustically modulated magnetic resonance imaging of gas-filled protein nanostructures
Gas-filled vesicles derived from photosynthetic microbes are shown to elicit magnetic resonance imaging contrast in vitro and in vivo with the potential for acoustically modulated multiplexing and molecular sensing.
- George J. Lu
- , Arash Farhadi
- & Mikhail G. Shapiro
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Article |
Selective layer-free blood serum ionogram based on ion-specific interactions with a nanotransistor
An ionogram based on a layer-free nanotransistor reveals the ability to selectively measure target ions in serum. Experimental and theoretical assessment of the mechanism of the surface–ion interaction is also revealed.
- R. Sivakumarasamy
- , R. Hartkamp
- & N. Clément
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Article |
Nitroaromatic detection and infrared communication from wild-type plants using plant nanobionics
Plants can be engineered to serve as self-powered pre-concentrators and autosamplers of analytes in ambient groundwater and as infrared communication platforms that can send information to a smartphone.
- Min Hao Wong
- , Juan P. Giraldo
- & Michael S. Strano
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Article |
Detection and imaging of quorum sensing in Pseudomonas aeruginosa biofilm communities by surface-enhanced resonance Raman scattering
Nanostructured plasmonic substrates are used for in situ, label-free detection, by surface-enhanced resonance Raman scattering spectroscopy, of quorum sensing in growing Pseudomonas aeruginosa biofilms.
- Gustavo Bodelón
- , Verónica Montes-García
- & Luis M. Liz-Marzán
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Article |
Phage-mediated counting by the naked eye of miRNA molecules at attomolar concentrations in a Petri dish
An ultrasensitive method that uses a genetically engineered bacteriophage to bind miRNA in a one-to-one manner allows the counting, by the naked eye, of miRNA molecules at attomolar concentrations on Petri dishes.
- Xin Zhou
- , Peng Cao
- & Chuanbin Mao
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News & Views |
Know your molecules
A new plasmonic sensing platform that not only allows the detection of ultrasmall quantities of biomolecules, but is also sensitive to their identity and conformational state, represents a significant advance in the study of biomolecular interactions.
- Na Liu
- & Annemarie Pucci
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Article |
Fano-resonant asymmetric metamaterials for ultrasensitive spectroscopy and identification of molecular monolayers
Plasmonic nanostructures are known to be an attractive platform for highly sensitive molecular sensors, although they often lack specificity. A plasmonic device with a sharp optical resonance tuned to biomolecules selectively captured on the surface of the device now offers a versatile yet highly specific platform for molecular sensing.
- Chihhui Wu
- , Alexander B. Khanikaev
- & Gennady Shvets
Renal clearable polyfluorophore nanosensors for early diagnosis of cancer and allograft rejection