Volume 7 Issue 10, October 2000


News & Views

  • News & Views |

    The recently solved crystal structures of the yeast and bovine poly(A) polymerases add to the growing list of high resolution RNA polymerase structures and provide a basis for understanding the specifics of template-independent RNA polymerization.

    • Paul D. Gershon
  • News & Views |

    The crystal structure of the CooA protein yields potential insight into the general mechanism of allostery within the CAP family of transcriptional regulators.

    • Michael K. Chan
  • News & Views |

    Limitations of the three putative mechanisms of amyloid fibril assembly for explaining Sup35 prion formation have led to the introduction of a fourth model — nucleated conformational conversion — that invokes oligomeric intermediates for initiation and assembly.

    • Jeffery W. Kelly


Picture Story

Review Article