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Statistical analysis is an essential part of clinical practice, since the very concept of evidence-based medicine hinges on sound interpretation of clinical data. Using the Scandinavian prostatectomy versus watchful waiting study as a practical example, Andrew Vickers presents two common errors: accepting the null hypothesis and misinterpreting the lower statistical power of overall versus cancer-specific survival, and warns of the dangers of forgetting these basic principles.
In this review, Renata Huzjan and colleagues discuss the utility of MRI and magnetic resonance spectroscopic imaging (MRSI) in the diagnosis and management of prostate cancer. MRI and MRSI provide important information on the extent, location and characteristics of tumors that is invaluable in pretreatment decision making. In order to fully exploit these techniques, a multidisciplinary approach is essential.
Priapism, particularly ischemic priapism, is uncommon in the general male population, but frequently occurs in men with hematologic dyscrasias such as sickle cell disease. In this review, Arthur Burnett focuses on the management of ischemic priapism, and stresses the need for prompt treatment in order to preserve erectile function in this group of men.
Premature ejaculation (PE) has a number of known causes, and the definition of what constitutes PE can differ. Several factors are used to assess the presence and extent of PE. Chris McMahon discusses the etiology and management of PE, and highlights the importance of selecting treatments that are appropriate to the cause of the condition
A number of different surgical techniques are used for the treatment of benign prostatic hyperplasia(BPH). This article by Liam Wilson and Peter Gilling reviews the different types of lasers available and their applications in ablation, coagulation and enucleation of the hyperplastic prostate for treating BPH.