Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
Two studies now provide insights into how surface contact and sensing stimulate the synthesis of c-di-GMP, which accelerates cell cycle progression and cell differentiation in Caulobacter crescentus.
This study shows that a high-fat diet and antibiotic treatment impair mitochondrial bioenergetics, which increases epithelial oxygenation and triggers dysbiosis and pre-inflammatory bowel disease.
This study reports that extensive copy number variations occur in the presence of azole antifungal drugs in Candida albicans, which might cause phenotypic and population-level heterogeneity observed in clinical isolates.
This study suggests that the enhanced pathogenicity following co-infection of corals with Vibrio coralliilyticus and Vibrio mediterranei is a side effect of competition sensing and the induced responses.
A recent study found that a bacterial metabolite is necessary to execute the cancer driving potential of ‘hotspot’ mutations in the p53 tumour suppressor gene.
A recent study reports that anthropogenic land use causes major changes in the diversity and taxonomic composition of reservoir hosts for pathogens, with implications for the emergence of zoonotic diseases.
This month’s Under the Lens discusses dual-view light-sheet microscopy and how its use has revealed the dynamics of bacterial biofilm development, a fundamental process found in bacteria.
Actinobacteria are versatile producers of bioactive natural products. In this Review, van Wezel and colleagues discuss ecological and genomic insights into the mechanisms governing natural product metabolism and how those insights can be translated into approaches for computational and experimental genome mining strategies that yield novel bioactive molecules, in particular antibiotics.
In this Review, Tsai and Cullen discuss how host epigenetic and epitranscriptomic processes regulate viral gene expression at the levels of chromatin and RNA function, respectively, and explore how viruses modify, avoid or utilize these processes in order to promote their replication or persistence.
In this Review, Rumbaugh and Sauer discuss the environmental cues and microorganism-derived signals that lead to the biofilm dispersal response, recent findings of matrix-degrading enzymes required for cells to liberate themselves from the biofilm matrix, novel insight into the mechanisms and regulation of dispersal, and the implications of these insights for biofilm control efforts.
Borrelia burgdorferi has a complex life cycle with several different hosts, causing Lyme disease when it infects humans. In this Review, Fikrig and colleagues discuss how B. burgdorferi infects and interacts with its tick vector to ensure onward transmission.
