Under the Lens

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  • This month’s Under the Lens discusses new strategies to image the spatial geography of microbial communities.

    • Mathew Stracy
    Under the Lens
  • This month’s Under the Lens discusses a few of the growing number of recent molecular simulation studies that have made substantial contributions towards our mechanistic understanding of the spike protein of SARS-CoV-2.

    • Conrado Pedebos
    • Syma Khalid
    Under the Lens
  • This month’s Under the Lens discusses how recent advanced microscopy studies have provided insights into key target-search mechanisms that allow the recombinase RecA to rapidly and efficiently find homology for DNA repair.

    • Emma Lalande
    • Hafez El Sayyed
    Under the Lens
  • This month’s Under the Lens discusses the potential of in silico feedback control applied to individual microbial cells, highlighting its use for study of single-cell dynamics and patterning behaviours.

    • Lisa Zillig
    • Harrison Steel
    Under the Lens
  • This month’s Under the Lens discusses the application of the quantitative image analysis software BiofilmQ to understand antibiotic-induced changes in Vibrio cholerae biofilms at single-cell resolution.

    • Divya Choudhary
    • Chloé J. Cassaro
    Under the Lens
  • This month’s Under the Lens discusses how combining cryo-electron tomography with cross-linking mass spectrometry has allowed elucidation of the mechanisms of transcription-coupled translation in bacteria.

    • Jan Böhning
    • Tanmay A. M. Bharat
    Under the Lens
  • This month’s Under the Lens discusses the application of high-speed atomic force microscopy to image fragile bacterial membrane vesicles by briefly touching them with a gentle tapping force, revealing species-specific heterogeneity in membrane vesicle size distribution linked to biological function.

    • Ruth Cohen-Khait
    Under the Lens
  • This month’s Under the Lens discusses dual-view light-sheet microscopy and how its use has revealed the dynamics of bacterial biofilm development, a fundamental process found in bacteria.

    • Suzanne C. Letham
    • Tanmay A. M. Bharat
    Under the Lens
  • This month’s Under the Lens discusses how structural studies of the SARS-CoV-2 spike glycoprotein might guide a path towards a vaccine.

    • Nawsad Alam
    • Matthew K. Higgins
    Under the Lens
  • This month’s Under the Lens discusses recent advances in spatial metabolomics and light-sheet microscopy for imaging the biogeography of host–microbiota interactions.

    • Manish S. Kushwah
    • Stephen Thorpe
    Under the Lens
  • This month’s Under the Lens discusses the use of single-molecule tracking in bacteria to study how CRISPR–Cas systems accurately and efficiently identify specific DNA sequences within viruses and other mobile genetic elements, thereby preventing their invasion.

    • Jarno Mäkelä
    • David J. Sherratt
    Under the Lens
  • This month’s Under the Lens discusses the application of light sheet fluorescence microscopy to observe the intestinal microbiota of live zebrafish, revealing unexpected host–microorganism interactions.

    • Sean C. Booth
    • William P. J. Smith
    Under the Lens
  • This month’s Under the Lens discusses how 3D fluorescence microscopy techniques are furthering the study of dynamic spatial organization and confinement in bacterial cells.

    • Jia Hui Khoo
    • Helen L. Miller
    Under the Lens
  • This month’s Under the Lens discusses the use of a novel label-free imaging method to study pilus dynamics at high spatial and temporal resolution.

    • Samuel J. Hickman
    Under the Lens
  • This month’s Under the Lens discusses progress towards bridging the resolution gap in correlative super-resolution light and electron microscopy, and highlights its application for visualizing bacterial infections.

    • Ian M. Dobbie
    Under the Lens
  • This month’s Under the Lens discusses the use of single-molecule tracking to study the effects and response of bacterial cells exposed to antibiotics.

    • Oliver J. Pambos
    • Achillefs N. Kapanidis
    Under the Lens