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Although GERD and functional dyspepsia are generally thought of as completely distinct disorders with unique symptoms and treatments, they are, in many ways, more similar than different and can overlap in the same individual. This Review, which focuses on the overlap of GERD with functional dyspepsia, describes similarities and differences with regards to the epidemiology, pathophysiology, diagnosis and treatment of these two disorders.
This Review summarizes present knowledge regarding the epidemiology, pathogenesis, diagnosis and treatment of oesophageal cancer. Important achievements are outlined and current controversies about the status of multimodal concepts and adequate therapy are discussed. Furthermore, the role of palliative care in patients with advanced, incurable tumours is highlighted.
Dietary factors are increasingly recognized to have an important role in triggering symptoms in a large proportion of patients with functional dyspepsia. This Review outlines the role of diet and specific foods and/or food components in symptom induction, summarizes potential mechanisms, and highlights the role that dietary interventions might have in treating functional dyspepsia.
Although polycystic liver disease is usually a benign disease, the symptoms can be debilitating in some patients, for whom surgery is an option. This Review discusses the latest advances in the diagnosis and management of polycystic liver disease.
