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Evidence from cohort studies and clinical trials supports an aetiological role of sugar-sweetened beverage (SSB) intake in the development of obesity and related chronic diseases. This Review provides an up-to-date view, considering the evidence, potential mechanisms and policy actions to reduce the global intake of SSBs.
Treatment of primary hypothyroidism is improving but many patients still report a reduced quality of life compared with healthy individuals. This Review discusses the management of primary hypothyroidism and the potential reasons for patient dissatisfaction with treatment.
Thyroid hormone is important during pregnancy, as it facilitates appropriate fetal development. Furthermore, thyroid dysfunction during pregnancy can negatively affect obstetric outcomes and maternal health. This Review discusses the evaluation and management of thyroid disorders in pregnancy and in the postpartum period.
This Review outlines the burden of type 2 diabetes mellitus and its complications in sub-Saharan Africa, including the pathogenesis, standards of care for treatment and preventive strategies.
