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Volume 15 Issue 11, November 2020

Lifelike signal processing

Cells and organisms adapt to signals by processing them through reaction networks that ultimately provide downstream functional responses and structural morphogenesis. Now Samanta, Walther and co-workers re-enact this signal processing in DNA protocells. They use genetically improved artificial metalloenzymes to convert signalling molecules into DNA interacting metabolites that induce downstream growth, functional adaptation and fusion processes inside and between protocells. The image is an artist's depiction of signal-molecule-triggered cellullar processes.

See Samanta et al.

Image: Johannes Richers. Cover Design: Bethany Vukomanovic.

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