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Hybrid quantum optomechanical systems interface a single two-level system with a macroscopic mechanical degree of freedom. In a microwire with a single embedded semiconductor quantum dot, not only can the wire vibration modulate the excitonic transition energy, but the optical drive of the quantum dot can also induce motion in the wire.
Manipulation of multiple connected quantum objects is mandatory for any scalable quantum information platform. Based on finely tuned virtual gate control, the integration of nearest-neighbour coupled semiconductor quantum dots in a 3 × 3 array enables 2D coherent spin control.
Compared to cancer nanomedicine, cancer immune nanomedicine presents unique challenges stemming from the complexity of the tumour responses to immunotherapy. This Perspective describes some of the factors contributing to this complexity and offers thoughts on how nanomedicine researchers can include them in their experimental design.
Tolerogenic dendritic cells inhibit inflammatory responses against self-antigens, offering a therapeutic strategy for autoimmune diseases. This Review describes the nanotechnology-based approaches available to target dendritic cells and induce tolerogenic properties, highlighting applications in organ transplantation, multiple sclerosis and diabetes mellitus.
New mechanistic insights into nanoparticle–plant interactions show that specifically designed silica nanoparticles have the potential to serve as an inexpensive, highly efficient, safe and tracelessly degradable alternative for pesticides.
Graphene–insulator–metal heterostructures show three orders of magnitude enhancement of the third-harmonic generation with respect to the bare graphene case.
Controlling immune cell activation would improve the efficiency of cell-based immunotherapies and reduce its associated risks. Here biodegradable particles are functionalized with DNA scaffolds for precise conjugation of a range of immunomodulating agents and applied ex vivo and in vivo for engineered immune cell modulation.
The conductance of a six-nanometre molecular wire can be reproducibly modulated by a factor of more than 1 × 104 at room temperature by enhancing destructive quantum interference amongst occupied molecular orbitals.
A highly porous carbon-based electrode with optimal mechanical and electrochemical properties is implemented in a bioelectronics device for the modulation of cardiomyocyte contraction in vitro, the excitation of heart and retina ex vivo and the stimulation of sciatic nerve in vivo.
Many-body interactions amongst interlayer excitons in a WSe2/MoSe2 heterobilayer give rise to a strong and tunable effective magnetic field enabling the control of the valley pseudospin.
The direct growth of large-area nanosheets of diverse phase-pure Ruddlesden–Popper perovskites enables the fabrication of arbitrary vertical heterostructures and multi-heterostructures of perovskites.
Two nanoparticle-based vaccines close to obtaining approval by the US Food and Drug Administration could represent a giant step in the fight against the COVID-19 pandemic.