Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Volume 11 Issue 10, October 2005

Acyldepsipeptides, a new class of antibiotics, have activity against Gram-positive bacteria-such as Enterococcus faecalis (shown here)-in vitro and in vivo (see page 1082). Photo by Nathan Shankar, University of Oklahoma. Courtesy of the Agricultural Research Service, US Department of Agriculture.

Volume 11 Issue 10

Subscribe

Editorial

Top of page ⤴

News

Top of page ⤴

Foreword

Top of page ⤴

Commentary

Top of page ⤴

Book Review

Top of page ⤴

News & Views

  • Antibiotic discovery has been stalled for well over a decade. The discovery of a new antibiotic with an unexpected mechanism of action could reinvigorate this lagging field (pages 1082–1087).

    • John S Blanchard
    News & Views

  • The hormone adiponectin is secreted from fat cells and increases sensitivity to insulin in muscle and liver; adiponectin increases resistance to metabolic disorders and, it now appears, may also protect heart tissue when blood flow is restricted (pages 1096–1103).

    • Koh-ichi Yuhki
    • Jun-ichi Kawabe
    • Fumitaka Ushikubi
    News & Views

  • In susceptible individuals, fasting can trigger an attack of acute porphyria—a syndrome caused by the neurotoxic effects of precursors to porphyrins. The mechanistic basis for this trigger is now uncovered.

    • John D Phillips
    • James P Kushner
    News & Views

  • A new approach to tumor therapy combines two problematic cancer-fighting tools: tumor-targeted T cells and gene therapy. The T cells deliver a gene therapy vector to tumor cells, ensuring their destruction (pages 1073–1081).

    • Cliona M Rooney
    News & Views

  • Results now emerge from a preclinical trial of a heat-shock protein inhibitor in a mouse model of neurodegenerative disease. The data indicate that targeting a misfolded protein for degradation may be a useful therapeutic strategy (pages 1088–1095).

    • Albert R La Spada
    • Patrick Weydt
    News & Views

  • Liver regeneration can occur by proliferation of two different cell types, but generally only one at a time is fully turned on. A factor that may specifically activate one of these cell types now comes to light.

    • Nelson Fausto
    News & Views
Top of page ⤴

Brief Communication

Top of page ⤴

Article

Top of page ⤴

Letter

Top of page ⤴

Technical Report

Top of page ⤴

Search

Advanced search

Quick links