Focus
Focus on Glia and Disease
- Focus issue:
- November 2007 Volume 10, No 11
Glia are critical to many brain disorders. Glial cells regulate brain vasculature and the blood-brain barrier, modulating ischemia and blood flow changes in response to neural activity. Moreover, they are important in brain repair after injury and contribute to neurodegenerative diseases. This special focus on glia and disease contains four reviews and two perspectives that highlight recent research in these areas and discuss how advances in understanding glial biology may lead to new treatments.
Introduction
Focus on Glia and Disease
Focus on glia and disease - pp1349
Sandra Aamodt
doi:10.1038/nn1107-1139
Full Text Focus on glia and disease | PDF (116 KB) - Focus on glia and disease
Perspectives
Focus on Glia and Disease
Dissecting demyelination - pp1351 - 1354
Robert H Miller & Sha Mi
doi:10.1038/nn1995
Abstract - Dissecting demyelination | Full Text - Dissecting demyelination | PDF (250 KB) - Dissecting demyelination
Focus on Glia and Disease
Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease - pp1355 - 1360
Christian S Lobsiger & Don W Cleveland
doi:10.1038/nn1988
Abstract - Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease | Full Text - Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease | PDF (561 KB) - Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease
Reviews
Focus on Glia and Disease
The neuropathic pain triad: neurons, immune cells and glia - pp1361 - 1368
Joachim Scholz & Clifford J Woolf
doi:10.1038/nn1992
Full Text - The neuropathic pain triad: neurons, immune cells and glia | PDF (413 KB) - The neuropathic pain triad: neurons, immune cells and glia
Focus on Glia and Disease
Glial regulation of the cerebral microvasculature - pp1369 - 1376
Costantino Iadecola & Maiken Nedergaard
doi:10.1038/nn2003
Abstract - Glial regulation of the cerebral microvasculature | Full Text - Glial regulation of the cerebral microvasculature | PDF (581 KB) - Glial regulation of the cerebral microvasculature
Focus on Glia and Disease
Astrocyte metabolism and signaling during brain ischemia - pp1377 - 1386
David J Rossi, James D Brady & Claudia Mohr
doi:10.1038/nn2004
Abstract - Astrocyte metabolism and signaling during brain ischemia | Full Text - Astrocyte metabolism and signaling during brain ischemia | PDF (1,377 KB) - Astrocyte metabolism and signaling during brain ischemia
Focus on Glia and Disease
Microglia: active sensor and versatile effector cells in the normal and pathologic brain - pp1387 - 1394
Uwe-Karsten Hanisch & Helmut Kettenmann
doi:10.1038/nn1997
Abstract - Microglia: active sensor and versatile effector cells in the normal and pathologic brain | Full Text - Microglia: active sensor and versatile effector cells in the normal and pathologic brain | PDF (963 KB) - Microglia: active sensor and versatile effector cells in the normal and pathologic brain
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