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Target-derived neurotrophins are important for cell survival. A new study shows that neurotrophins activate different MAP kinase signaling pathways depending on whether they are applied to cell bodies or axon terminals, regulating distinct sets of genes.
Segregation of an image into figure and ground is an important step in visual processing. Two new papers show that responses in human and monkey brain areas known to be involved in shape perception depend critically on whether a region is perceived as figure or ground.
A newly identified Alzheimer's mutation leads to the suggestion that protofibril intermediates in amyloid plaque formation may be a crucial factor in pathogenicity.