Jennie Vallis

Focus on neuroscience methods

Our publishing model is changing

Open Access options available from January 2021, read more

Latest Research

  • Article |

    The authors demonstrate the presence of SARS-CoV-2 in the nasopharynx and brain, suggesting that the virus is present in the CNS and may enter through the olfactory mucosa, exploiting the close vicinity of olfactory mucosal, endothelial and nervous tissue.

    • Jenny Meinhardt
    • , Josefine Radke
    • , Carsten Dittmayer
    • , Jonas Franz
    • , Carolina Thomas
    • , Ronja Mothes
    • , Michael Laue
    • , Julia Schneider
    • , Sebastian Brünink
    • , Selina Greuel
    • , Malte Lehmann
    • , Olga Hassan
    • , Tom Aschman
    • , Elisa Schumann
    • , Robert Lorenz Chua
    • , Christian Conrad
    • , Roland Eils
    • , Werner Stenzel
    • , Marc Windgassen
    • , Larissa Rößler
    • , Hans-Hilmar Goebel
    • , Hans R. Gelderblom
    • , Hubert Martin
    • , Andreas Nitsche
    • , Walter J. Schulz-Schaeffer
    • , Samy Hakroush
    • , Martin S. Winkler
    • , Björn Tampe
    • , Franziska Scheibe
    • , Péter Körtvélyessy
    • , Dirk Reinhold
    • , Britta Siegmund
    • , Anja A. Kühl
    • , Sefer Elezkurtaj
    • , David Horst
    • , Lars Oesterhelweg
    • , Michael Tsokos
    • , Barbara Ingold-Heppner
    • , Christine Stadelmann
    • , Christian Drosten
    • , Victor Max Corman
    • , Helena Radbruch
    •  & Frank L. Heppner
  • Article |

    When people are isolated, they crave social interactions. Midbrain craving regions were activated by food in hungry people, and by social interactions in people mandated to be isolated.

    • Livia Tomova
    • , Kimberly L. Wang
    • , Todd Thompson
    • , Gillian A. Matthews
    • , Atsushi Takahashi
    • , Kay M. Tye
    •  & Rebecca Saxe
  • Article |

    Pacheco et al. present new methods for the unbiased recording and cataloging of sensory activity throughout the Drosophila brain and across trials and individuals. They find auditory activity is temporally diverse but present in neurons throughout nearly all central brain regions.

    • Diego A. Pacheco
    • , Stephan Y. Thiberge
    • , Eftychios Pnevmatikakis
    •  & Mala Murthy
  • Article |

    Ong et al. analyzed behavior, gaze patterns and neuronal activity of monkeys playing the game ‘chicken’. Monkeys seemed to develop models of the behavior of the partner, and neurons in the mSTS and the ACCg signaled strategic information to guide their decisions.

    • Wei Song Ong
    • , Seth Madlon-Kay
    •  & Michael L. Platt

News & Comment

  • News & Views |

    One of the mechanisms driving aging and neurodegenerative diseases is the accumulation of senescent cells, while their elimination mitigates age-related decline. A new report details how, with aging, changes in the dentate gyrus microenvironment lead to natural-killer-cell-mediated clearance of neurogenic senescent cells, resulting in cognitive decline.

    • Nurit Papismadov
    •  & Valery Krizhanovsky
  • Editorial |

    In this special issue, we present a series of reviews, perspectives and commentaries that highlight advances in methods and analytical approaches and provide guidelines and best practices in various areas of neuroscience.

  • News & Views |

    Network neuroscientists envision the brain as a network of nodes (regions) linked via edges (connections). A long-held assumption is that node-centric interactions are the primary phenomena of interest. Faskowitz et al. introduce a novel edge-centric framework with the potential to usher in a new era of discovery in connectomics research.

    • Lucina Q. Uddin
  • News & Views |

    Chiot and colleagues investigated whether peripheral macrophages play a role in amyotrophic lateral sclerosis (ALS) pathology, finding that macrophages along peripheral motor neuron axons react to neurodegeneration. Modifying reactive oxygen species (ROS) signaling in peripheral macrophages, using bone marrow cell replacement, reduces both macrophage and microglia inflammatory response, delays pathology and increases survival in ALS mouse models.

    • P. Hande Özdinler
  • News & Views |

    By building a richer behavioral vocabulary, Wiltschko et al. tease apart subtle differences in how pharmacological agents affect animal behavior, mapping on- and off-target effects of drugs with improved precision.

    • Ann Kennedy
  • News & Views |

    Abrupt spatial changes in anatomic and functional properties of the brain demarcate boundaries between discrete functional areas. While previous work has identified these boundaries in cortex, a new study by Tian et al. applies this approach for the first time to subcortical structures within the in vivo human brain.

    • Evan M. Gordon

Nature events Directory