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Here, using hypergraph modeling the authors show that surprising research (in terms of unexpected combinations of research contents and contexts) is associated with impact and arises from scientific outsiders solving problems in distant disciplines.
Earth’s inner core is heterogeneous and anisotropic. A new study based on computational simulation reveals the presence of ionic hydrogen flux in iron crystals, driven by the dipole geomagnetic field, which promotes the formation of observed inner core structure.
Ecosystem responses to prehistoric sea-ice loss are poorly known. Using marine sedimentary ancient DNA form the Bering Sea covering the last ~20,000 years, this study reveals a transition from a sea ice-adapted ecosystem, characterized by diatoms, copepods and codfish, to an ice-free Holocene with cyanobacteria, salmon and herring.
Material designs with multicolor circularly polarized emissions are desirable for photonic applications. Here, the authors report supramolecular glasses based on self-assembled chiral metal–organic complexes with color-tunable circularly polarized afterglow.
Induced proximity can be used to control diverse cellular processes. Here, the authors develop nanobody-based proximity inducers called SNACIPs, which can be used to regulate either tagged or endogenous proteins, and demonstrate their use in blocking microtubule nucleation for tumour growth inhibition in vivo.
Understanding phonon-induced relaxation in molecular qubits is a crucial step in realizing their application potential. Garlatti at al. use a combination of inelastic X-ray scattering and density functional theory to investigate the role of low-energy phonons on spin relaxation of a prototypical molecular qubit.
Mechanisms of sleep remain elusive. Here, authors developed mouse sleep fMRI based on simultaneous electrophysiology and mapped global and sequential state transition patterns, together with global patterns triggered by SWRs in NREM and awake states.
Root exudates display a diurnal signature, change with growth environment, and can be divided into a core metabolome common to multiple plant species, and specialized exudates produced by distinct species.
Bio-degradation of poly(butylene adipate-co-terephthalate) is an attractive tactic but requires an effective hydrolytic enzyme. Here, the authors demonstrate that cutinases are highly potent PBAT-decomposing enzymes and their mechanism is proposed based on substrate-binding mode.
In this study, the authors perform a meta-analysis of COVID-19 vaccine effectiveness studies and compare observed protection against severe disease with model-based estimates of neutralising antibody titres. Their results show that SARS-CoV-2 antibody titres are predictive of protection against severe COVID-19 disease.
Transmembrane signaling is the core adaptation in nature that allows cells to communicate. Here, the authors engineer signaling through the lipid bilayer using chemical, synthetic receptors for their use in the design of artificial cells.
A nonreciprocal critical current is known as the superconducting diode effect (SDE). Here, the authors use SQUID-on-tip to study SDE in a EuS/Nb bilayer and find that the stray field from magnetized EuS creates screening currents in the Nb, which lead to SDE by affecting vortex flow dynamics.
Many transcriptomic pathways in the liver show circadian rhythms, which have been reported to be disrupted in aged mice. Here the authors report that the expression of transcription factor Egr-1 decreases and its rhythm is shifted with age in the liver of male mice, and that deletion of Egr-1 results in increased liver fat accumulation.
Space-charge layers are believed to profoundly influence the interfaces in all-solid-state Li batteries. Here, the authors provide atomic scale insights into this phenomenon, and discover that its impact could be fundamentally different from commonly believed.
Polarons are quasi-particles that emerge when impurity particle is mixed with the low-energy excitations of a medium. Here the authors study the case of atom-ion quantum mixtures and identify three separate bipolaronic regimes which can arise depending on the interaction range and strength.
The existence of multicellular systems relies on coordinated cell motion in three dimensions. Here, cell migration in rotating spherical tissues is shown to exhibit a collective mode with a single-wavelength velocity wave, which arises from the effect of curvature on the flocking behavior of cells on a spherical surface.
The weathering alkalinity flux from mid-latitudes to the ocean will be strongly altered by climate warming by 2100. Under different emissions scenarios either a strengthening or a weakening of the flux and thus of the oceanic CO2 buffer is predicted.
Early detection of multiple cancers through a single method could be clinically important. Here the authors report the diagnostic performance for early detection for multiple cancers using surface-enhanced Raman spectroscopy (SERS) profiles of exosomes from a single blood test and artificial intelligence in a retrospective study design.
Sliding and twisting of van der Waals layers can produce fascinating physical phenomena. Here, authors show that moiré polar domains in bilayer hBN give rise to a topologically non-trivial winding of the polarization field, forming networks of merons and antimerons.
Modification of RNA with m6A has been shown to be important during spermatogenesis. Here they identify post-transcriptional functions of PRRC2A, showing it promotes transcriptome transition from spermatogonia to spermatocytes and the translation of genes related to cell division.