Nature Biotechnology

Volume 22 Issue 1, January 2004

Characteristic, reddish colonies of the purple photosynthetic bacterium Rhodopseudomonas palustris superimposed on a picture of its rod-shaped cells visualized under the light microscope. This issue reports the complete sequence of R. pulustris, a metabolically highly versatile microorganism (see pp 55-61).

Volume 22 Issue 1

Editorial

The one that got away

Editorial 01 Jan 2004

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News

China approves first gene therapy

Sue Pearson
Hepeng Jia
Keiko Kandachi
News 01 Jan 2004
Vatican debates agbiotech

Jeffrey L. Fox
News 01 Jan 2004
UK to pursue contract clinical trials

Sabine Louët
News 01 Jan 2004
Cancer trials get set for biomarkers

Aaron Bouchie
News 01 Jan 2004
Chile launches policy to boost biotech

Claudia Orellana
News 01 Jan 2004
Nasdaq dilutes its biotech index

Emma Dorey
News 01 Jan 2004

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News in Brief

News In Brief

News in Brief 01 Jan 2004

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News Feature

Signal transduction inhibitors—a work in progress

Is the race to take protein kinase inhibitors to market compromising their success in the clinic?

Joseph Becker
News Feature 01 Jan 2004

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Correspondence

Health impact of nanomaterials?

Peter H M Hoet
Abderrahim Nemmar
Benoit Nemery
Correspondence 01 Jan 2004
Realities for Latin American and Caribbean biotech

Rafael Rangel-Aldao
Correspondence 01 Jan 2004

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Commentary

The emerging role of academia in commercializing innovation

Shreefal Mehta
Commentary 01 Jan 2004
Do cloned mammals skip a reprogramming step?

Josef Fulka Jr.
Norikazu Miyashita
Atsuo Ogura
Commentary 01 Jan 2004

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Fools Corner

How do your stocks really perform?

Tom Jacobs
Fools Corner 01 Jan 2004

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Book Review

Hybrids abounding

Steven H Strauss
Stephen P DiFazio
Book Review 01 Jan 2004

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Feature

Old dogma, new tricks—21st Century phage therapy

As antibiotic resistant bacteria threaten a public health crisis, biotechnology is turning to bacteriophages, nature's tiniest viruses. But can phage therapy overcome its historical baggage?

Karl Thiel
Feature 01 Jan 2004

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News & Views

The biological magic behind the bullets

Testing the relative fitness of thousands of yeast strains helps determine pathways and proteins targeted by small-molecule drugs

Brent R Stockwell
News & Views 01 Jan 2004
Cancer surgery joins the dots

Quantum dots show potential as a tool for imaging sentinel lymph nodes and guiding surgery.

Roger F Uren
News & Views 01 Jan 2004
Rain or shine—a phototroph that delivers

The complete genome sequence of the bacterium Rhodopseudomonas palustris reveals well rounded metabolic and biodegradation capabilities.

Judy D Wall
News & Views 01 Jan 2004
Unnatural selection of cultured human ES cells?

Human embryonic stem (ES) cells maintained in culture can develop chromosomal abnormalities.

Martin F Pera
News & Views 01 Jan 2004
Protein interaction maps on the fly

A protein interaction map for the fruit fly Drosophila melanogaster promises to facilitate functional analysis of many eukaryotic proteins.

Peter Uetz
Michael J Pankratz
News & Views 01 Jan 2004
Research notes

News & Views 01 Jan 2004

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Perspective

The use of nanocrystals in biological detection

Paul Alivisatos
Perspective 02 Jan 2003

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Brief Communication

Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells

Jonathan S Draper
Kath Smith
Peter W Andrews
Brief Communication 07 Dec 2003

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Article

Complete genome sequence of the metabolically versatile photosynthetic bacterium Rhodopseudomonas palustris

Frank W Larimer
Patrick Chain
Caroline S Harwood
Article Open Access 14 Dec 2003
Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways

Ainslie B Parsons
Renée L Brost
Charles Boone
Article 07 Dec 2003
Systemic tumor targeting and killing by Sindbis viral vectors

Jen-Chieh Tseng
Brandi Levin
Daniel Meruelo
Article 30 Nov 2003
Gaining confidence in high-throughput protein interaction networks

Joel S Bader
Amitabha Chaudhuri
John Chant
Article 14 Dec 2003
Principles of transcriptional control in the metabolic network of Saccharomyces cerevisiae

Jan Ihmels
Ronen Levy
Naama Barkai
Article 30 Nov 2003

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Letter

Near-infrared fluorescent type II quantum dots for sentinel lymph node mapping

Sungjee Kim
Yong Taik Lim
John V Frangioni

Collection:

Nobel Prize in Chemistry 2023
Letter 07 Dec 2003
Unraveling protein interaction networks with near-optimal efficiency

Michael Lappe
Liisa Holm
Letter 07 Dec 2003
Systematic identification of sense-antisense transcripts in mammalian cells

Øystein Røsok
Mouldy Sioud
Letter 14 Dec 2003

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Patents

Patent protection for protein structure analysis

Three national patent offices have consulted on patents that cover protein three-dimensional structural data and pharmacophores, with significant implications for the biotechnology industry.

Itsuki Shimbo
Rie Nakajima
Koichi Sumikura
Patents 01 Jan 2004
Recent patent applications in proteomics

Patents 01 Jan 2004

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People

People

People 01 Jan 2004

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New on the Market

Lab automation & Proteomics

New on the Market 01 Jan 2004

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Quiz

The Nature Biotechnology 2004 New Year Quiz

Quiz 01 Jan 2004

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Careers and Recruitment

Does your chairman need to be Superman?

To find the right chairman for your biotechnology company, brush up on your chemistry skills.

Nicolas Hollanders
Careers and Recruitment 01 Jan 2004

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