Articles in 2023

New algorithms allow researchers to decode words the brain is hearing with a non-invasive method, outside the scalp.

The number of publications in artificial intelligence (AI) has been increasing exponentially and staying on top of progress in the field is a challenging task. Krenn and colleagues model the evolution of the growing AI literature as a semantic network and use it to benchmark several machine learning methods that can predict promising research directions in AI.

AlphaFold2 has revolutionized bioinformatics, but its ability to predict protein structures with high accuracy comes at the price of a costly database search for multiple sequence alignments. Fang and colleagues pre-train a large-scale protein language model and use it in conjunction with AlphaFold2 as a fully trainable and efficient model for structure prediction.

It is widely known that AI-based recommendation systems on social media and news websites can isolate humans from diverse information, eventually trapping them in so-called information cocoons, where they are exposed to a narrow range of viewpoints. Li et al. introduce an adaptive information dynamics model to uncover the origin of information cocoons in complex human–AI interaction systems, and test their findings on two large real-world datasets.

Deep learning can help develop non-invasive technology for decoding speech from brain activity, which could improve the lives of patients with brain injuries. Défossez et al. report a contrastive-learning approach to decode speech listening from human participants, using public databases of recordings based on non-invasive magnetic and electrical measurements.

Online matching platforms are increasingly used for applications with positive social impact such as matching blood donors with recipients, where matching algorithms need to balance fairness with an efficiency objective. The authors demonstrate, both in computational simulations and using real data from the Facebook Blood Donations tool, that introducing a simple online matching policy can substantially increase the likelihood of donor action.

Fine motor skill recovery in hand rehabilitation is a challenge due to limited finger movement sensing and closed-loop control algorithms in existing rehabilitation gloves. Sui et al. develop a soft-packaged rehabilitation glove, integrating sensing, actuation, a human–machine interface, power, electronics and a closed-loop algorithm. The glove aids patients after a stroke to recover fine motor skills of the fingers in a portable manner.

Efficient quantum-control protocols are required to utilize the full power of quantum computers. A new reinforcement learning approach can realize efficient, robust control of quantum many-body states, promising a practical advance in harnessing present-day quantum technologies.

Identifying interventions that can induce a desired effect is challenging owing to the combinatorial number of possible choices in design space. Zhang and colleagues propose an active learning approach with theoretical guarantees to discover optimal interventions in causal models, and demonstrate the framework in the context of genetic perturbation design using single-cell transcriptomic data.

State-of-the-art image reconstruction for multispectral optoacoustic tomography is currently too slow for clinical applications. Dehner, Zahnd et al. propose a deep learning framework to reconstruct optoacoustic images in real-time while maintaining similar quality.

The recent accessibility of large language models brought them into contact with a large number of users and, due to the social nature of language, it is hard to avoid prescribing human characteristics such as intentions to a chatbot. Pataranutaporn and colleagues investigated how framing a bot as helpful or manipulative can influence this perception and the behaviour of the humans that interact with it.

Despite their efficiency advantages, the performance of photonic neural networks is hampered by the accumulation of inherent systematic errors. Zheng et al. propose a dual backpropagation training approach, which allows the network to adapt to systematic errors, thus outperforming state-of-the-art in situ training approaches.

Advances in DNA nanoengineering promise the development of new computing devices within biological systems, with applications in nanoscale sensing, diagnostics and therapeutics.

Local methods of explainable artificial intelligence identify where important features or inputs occur, while global methods try to understand what features or concepts have been learned by a model. The authors propose a concept-level explanation method that bridges the local and global perspectives, enabling more comprehensive and human-understandable explanations.

With the advances in neural language models, the question arises if some models align better with human processing than others. Golan et al. identify sentences that language models disagree about and use them to compare the shortcomings of different language models.

An outstanding challenge in materials science is doing large-scale simulations with complex electron interactions. Deng and colleagues introduce a universal graph neural network-based interatomic potential integrating atomic magnetic moments as charge constraints, which allows for capturing subtle chemical properties in several lithium-based solid-state materials