News & Comment

Pharmaceutical companies continue to advocate for the use of in vitro models towards the reduction of animal use in drug discovery and development while acknowledging that further advancements are needed to heighten the models’ current state of readiness.

When designing diagnostic assays intended for point-of-care use, more attention should be given to simplicity of operation.

Increasingly physiological in vitro models and techniques for measuring forces at multiple scales are enabling unanticipated findings in tissue mechanopathology.

The management of health and of disease conditions will eventually be supported by ever more integrated and less conspicuous wireless bioelectronic devices designed to continuously monitor multiple biomarkers.

Leverage curiosity, open-mindedness and the deliberate seeking of feedback.

Leveraging or improving established technology for clinical imaging to extract additional physiological information can enhance the quality of the subsequent assessments and widen the technology’s uses.

We provide a roadmap for overhauling faculty-hiring processes to eliminate barriers of entry to historically excluded groups.

Established reasoning behind yearly changes in impact factors is mostly flawed.

The development of machine-learning systems for safer, robust and fairer outcomes should leverage fine-tuning, generalization, explainability and metrics of uncertainty.

The continuing optimization of the safety and applicability of CRISPR for ex vivo genome editing will broaden the prospects of cell therapies.

Bionic hands exemplify the challenges of developing neuroprostheses that can be embodied.

New strategies for enhancing the sensitivity and resolution of contrast in magnetic resonance imaging will broaden its applicability.

The consequences of their use will be far reaching.

At first glance, some research articles published in the journal may appear to lack substantial novelty.