Volume 50 Issue 3, March 2021

Non-invasive drug administration via micropipette

The micropipette-guided drug administration (MDA) method was originally developed as a less-stressful alternative to oral gavage for delivering drugs to laboratory mice. New research published this month evaluates the MDA approach as a non-invasive alternative to intraperitoneal injections to deliver ligands for DREADD systems, a chemogenetic technique for manipulating neuronal activity in behaving animals.

See Schalbetter et al.

IMAGE: Marina Spence. COVER DESIGN: Marina Spence.