Volume 50 Issue 2, February 2021
Sterile hybrids for inducing pseudopregnancy
To induce pseudopregnancy in female mice, they need to be mated with males that are sterile and can’t cause actual pregnancy. Sterility can be achieved through surgical vasectomy or the use of genetically modified males but in the former case, there can be pain and discomfort involved and in the latter, unusable animals. A new research article proposes a potential refinement and reduction for inducing pseudopregnancy: mating females with naturally sterile hybrid male mice.
See Preece et al.
IMAGE: Mike Kemp / Tetra Images / Getty. COVER DESIGN: Allen Beattie.
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