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Recent genome editing techniques have substantially simplified the generation of genetically modified mice. A new study combines adeno-associated viruses (AAV) and electroporation to generate a robust pipeline to deliver CRISPR-Cas reagents into mouse embryos.
This Review provides a comprehensive overview of currently available animal models of postpartum hemorrhage, comparing their anatomy and physiology and highlighting their advantages and limitations to support therapeutic development for this condition.
No, we are not talking about a new dish for dinner, but a study representing an emerging research field. Psilocybin research is gaining momentum, and zebrafish behavioral neuroscience research has been exponentially expanding. At the intersection of these two research fields is a recent paper that utilized high-tech video-tracking to detect behavioral changes induced by this psychoactive drug in larval zebrafish.
Biomedical research is experiencing a data explosion, but this does not guarantee building upon knowledge gained from previous experiments. Without appropriate metadata, data can be wasted, especially in animal research. A minimal metadata set is proposed to enable data repurposing, aligning with ARRIVE 2.0 guidelines and making in vivo data FAIR-compliant.
