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Immunological memory

Eight specially commissioned articles survey the topic of immunological memory.

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Editorial

Focus on immunological memory

Remembering things past p461

doi:10.1038/ni0611-461

Memory is the signature property of the adaptive response, and vaccination is a hugely important medical intervention—understanding the former will help perfect the latter.


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Overview

Focus on immunological memory

Understand memory, design better vaccines pp463 - 465

Michael J Bevan

doi:10.1038/ni.2041

Naive lymphocytes have a finite lifespan and are continually replaced by input from generative organs. In contrast, memory cells or their progeny can last a lifetime. The expanded populations of memory cells and their more widespread distribution provide protection against recurrent infection.


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Reviews

Focus on immunological memory

Origins of CD4+ effector and central memory T cells pp467 - 471

Marion Pepper & Marc K Jenkins

doi:10.1038/ni.2038




Focus on immunological memory

Regional and mucosal memory T cells pp485 - 491

Brian S Sheridan & Leo Lefrançois

doi:10.1038/ni.2029


Focus on immunological memory

T cell exhaustion pp492 - 499

E John Wherry

doi:10.1038/ni.2035


Focus on immunological memory

Natural killer cell memory pp500 - 508

Silke Paust & Ulrich H von Andrian

doi:10.1038/ni.2032


Focus on immunological memory

Immunological mechanisms of vaccination pp509 - 517

Bali Pulendran & Rafi Ahmed

doi:10.1038/ni.2039


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Research Highlights

Focus on immunological memory

Research Highlights p518

doi:10.1038/ni0611-518


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