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Collection: Newly-Discovered Bioactive Natural Product
In its long history of over 60 years The Journal of Antibiotics has been publishing many reports on the newly identified, or isolated bioactive natural products and utilized by many researchers as a latest catalogue of novel, bioactive natural products. Featuring this continued tradition of The Journal of Antibiotics, here we introduce select papers reporting newly-discovered or produced bioactive natural products.
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AlbaflavenolB, a new sesquiterpene isolated from the terrestrial actinomycete, Streptomyces sp.
Ritesh Raju, Oleksandr Gromyko, Viktor Fedorenko, Andriy Luzketskyy and Rolf Müller
The Journal of Antibiotics 68 286-288; (April 2015) | doi:10.1038/ja.2014.138
Androprostamines A and B, the new anti-prostate cancer agents produced by Streptomyces sp MK932-CF8
Yohko Yamazaki, Tetsuya Someno, Masayuki Igarashi, Naoko Kinoshita, Masaki Hatano, Manabu Kawada, Isao Momose and Akio Nomoto
The Journal of Antibiotics 68 279-285; (April 2015) | doi:10.1038/ja.2014.135
Isolation and structure elucidation of the nucleoside antibiotic strepturidin from Streptomyces albus DSM 40763
Alexander Pesic, Britta Steinhaus, Sebastian Kemper, Jonny Nachtigall, Hans Jürgen Kutzner, Gerhard Höfle and Roderich D Süssmuth
The Journal of Antibiotics 67 471-477; (June 2014) | doi:10.1038/ja.2014.16
Mangromicins A and B: structure and antitrypanosomal activity of two new cyclopentadecane compounds from Lechevalieria aerocolonigenes K10-0216
Takuji Nakashima, Masato Iwatsuki, Junya Ochiai, Yoshiyuki Kamiya, Kenichiro Nagai, Atsuko Matsumoto, Aki Ishiyama, Kazuhiko Otoguro, Kazuro Shiomi, Yoko Takahashi and Satoshi Ōmura
The Journal of Antibiotics 67 253-260; (March 2014) | doi:10.1038/ja.2013.129
Pedopeptins, novel inhibitors of LPS: Taxonomy of producing organism, fermentation, isolation, physicochemical properties and structural elucidation
Yuki Hirota-Takahata, Shiho Kozuma, Nahoki Kuraya, Daisuke Fukuda, Mutsuo Nakajima and Osamu Ando
The Journal of Antibiotics 67 243-251; (March 2014) | doi:10.1038/ja.2013.122
New chaetoglobosin derivatives, MBJ-0038, MBJ-0039 and MBJ-0040, isolated from the fungus Chaetomium sp f24230 FREE
Teppei Kawahara, Masashi Itoh, Miho Izumikawa, Noriaki Sakata, Toshio Tsuchida and Kazuo Shin-ya
The Journal of Antibiotics 67 727-730; (December 2013) | doi:10.1038/ja.2013.75
Cabanillasin, a new antifungal metabolite, produced by entomopathogenic Xenorhabdus cabanillasii JM26 FREE
Jessica Houard, André Aumelas, Thierry Noël, Sylvie Pages, Alain Givaudan, Valérie Fitton-Ouhabi, Philippe Villain-Guillot and Maxime Gualtieri
The Journal of Antibiotics 66 617-620 (October 2013) | doi:10.1038/ja.2013.58
Diorcinols B-E, new prenylateddiphenyl ethers from the marine-derived fungus Aspergillus versicolor ZLN-60 FREE
Huquan Gao, Lina Zhou, Shengxin Cai, Guojian Zhang, Tianjiao Zhu, Qianqun Gu and Dehai Li
The Journal of Antibiotics 66 539-542 (September 2013) | doi:10.1038/ja.2013.40
KB425796-A, a novel antifungal antibiotic produced by Paenibacillus sp 530603 FREE
Hirohito Kai, Midori Yamashita, Shigehiro Takase, Michizane Hashimoto, Hideyuki Muramatsu, Ikuko Nakamura, Koji Yoshikawa, Masami Ezaki, Kumiko Nitta, Masato Watanabe, Noriaki Inamura and Akihiko Fujie
The Journal of Antibiotics 66 465-471 (August 2013) | doi:10.1038/ja.2013.63
Isolation and synthesis of falcitidin, a novel myxobacterial-derived acyltetrapeptide with activity against the malaria target falcipain-2 FREE
Brinda Somanadhan, Santosh R Kotturi, Chung Yan Leong, Robert P Glover, Yicun Huang, Horst Flotow, Antony D Buss, Martin J Lear and Mark S Butler
The Journal of Antibiotics 66 259-264 (May 2013) | doi:10.1038/ja.2012.123
Migracins A and B, new inhibitors of cancer cell migration, produced by Streptomyces sp. FREE
Yuhei Arai, Hironobu Iinuma, Yoko Ikeda, Masayuki Igarashi, Masaki Hatano, Naoko Kinoshita, Tamami Ukaji, Siro Simizu and Kazuo Umezawa
The Journal of Antibiotics 66 225-230 (April 2013) | doi:10.1038/ja.2012.112
Isolation and characterization of NAI-802, a new lantibiotic produced by two different Actinoplanes strains FREE
Matteo Simone, Paolo Monciardini, Eleonora Gaspari, Stefano Donadio and Sonia I Maffioli
The Journal of Antibiotics 66 73-78 (February 2013) | doi:10.1038/ja.2012.92
Spirohexalines, new inhibitors of bacterial undecaprenyl pyrophosphate synthase, produced by Penicillium brasilianum FKI-3368 FREE
Junji Inokoshi, Yuichiro Nakamura, Zhang Hongbin, Ryuji Uchida, Ken-ichi Nonaka, Rokuro Masuma and Hiroshi Tomoda
The Journal of Antibiotics 66 37-41 (January 2013) | doi:10.1038/ja.2012.83
New diketopiperazine derivatives from a deep-sea-derived Nocardiopsis alba SCSIO 03039 FREE
Qingbo Zhang, Sumei Li, Yuchan Chen, Xinpeng Tian, Haibo Zhang, Guangtao Zhang, Yiguang Zhu, Si Zhang, Weimin Zhang and Changsheng Zhang
The Journal of Antibiotics 66 31-36 (January 2013) | doi:10.1038/ja.2012.88
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