Multi-immersion mirror objectives
Neurons in the mouse hippocampus imaged with the Schmidt objective. Voigt et al. develop a multi-immersion objective based on a mirror instead of a lens.
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KARR-seq maps higher-order RNA structures and RNA–RNA interactions across the transcriptome
Mapping higher-order RNA structures and intermolecular RNA–RNA interactions throughout the transcriptome is critical for understanding RNA functions. We developed KARR-seq, a chemical-assisted RNA proximity capture and sequencing technology that enables sensitive and accurate detection of the RNA structurome and functional RNA–RNA interactions.
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