Focus
Focus on Chromatin
- Focus issue:
- November 2007 Volume 14, No 11
In eukaryotes, the packaging of DNA by histones into chromatin has profound effects on transcription and other nuclear processes. Far from being a uniform set of 'beads on a string', chromatin structure is remodeled and even modified, altering the accessibility of packaged genes to the factors involved in their regulation. This special focus on chromatin features an Overview, six Reviews and a Perspective that describe how chromatin is built and subsequently altered at various structural levels, and the impact of these events on fundamental biological processes involving DNA.
Overview
Focus on Chromatin
Chromatin rules - pp986 - 988
Roger D Kornberg & Yahli Lorch
doi:10.1038/nsmb1107-986
Perspective
Focus on Chromatin
Chromatin remodeling: insights and intrigue from single-molecule studies - pp989 - 996
Bradley R Cairns
doi:10.1038/nsmb1333
Reviews
Focus on Chromatin
Histone chaperones: an escort network regulating histone traffic - pp997 - 1007
Leanne De Koning, Armelle Corpet, James E Haber & Geneviève Almouzni
doi:10.1038/nsmb1318
Focus on Chromatin
Covalent modifications of histones during development and disease pathogenesis - pp1008 - 1016
Sukesh R Bhaumik, Edwin Smith & Ali Shilatifard
doi:10.1038/nsmb1337
Focus on Chromatin
Cross-regulation of histone modifications - pp1017 - 1024
John A Latham & Sharon Y R Dent
doi:10.1038/nsmb1307
Focus on Chromatin
How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers - pp1025 - 1040
Sean D Taverna, Haitao Li, Alexander J Ruthenburg, C David Allis & Dinshaw J Patel
doi:10.1038/nsmb1338
Focus on Chromatin
Transcription and RNAi in heterochromatic gene silencing - pp1041 - 1048
Marc Bühler & Danesh Moazed
doi:10.1038/nsmb1315
Focus on Chromatin
Gene regulation through nuclear organization - pp1049 - 1055
Tom Sexton, Heiko Schober, Peter Fraser & Susan M Gasser
doi:10.1038/nsmb1324
Primers
Focus on Chromatin
Primers on chromatin - pp1110 - 1115
Sabbi Lall
doi:10.1038/nsmb1107-1110