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Chronic kidney disease

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Chronic kidney disease (CKD) describes several conditions characterised by progressive kidney damage and loss of function. CKD is known to affect millions worldwide and is growing in prevalence due to a rise in the population effected by major risk factors, including obesity, diabetes, and ageing. Causes can be both environmental and genetic, with the most common being diabetes, hypertension, and glomerulonephritis.

The disease is classified into 5 stages based on the severity of the abnormal reduction in glomerular filtration rate a patient experiences. At the early stages (1-3), patients have mild to moderate loss of kidney function, whereas stage 5 is also known as end stage renal disease and patients at this stage will most likely require kidney transplant.

Early diagnosis is vital to slow disease progression and to ensure patient quality of life is preserved as much as possible, however, with patients often displaying limited symptoms during the early stages of the disease, many may be unaware of their condition until it is advanced.

This Collection aims to bring together primary research papers that describe methods for improved CKD early diagnosis, monitoring or treatment or provide mechanistic insight into the underlying causes of the disease.

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kidney with disease

Editors

Giuseppe Coppolino, PhD, “Magna Graecia” University of Catanzaro, Italy

Giuseppe Coppolino is Associate Professor of Nephrology at “Magna Graecia” University of Catanzaro, Italy. His research interests comprise the cardiovascular (CV) complications of renal diseases and CV risk in CKD, new renal biomarkers of AKI and CKD. Prof. Dr. Coppolino has been an Editorial Board Member for Scientific Reports since 2022.

 

 

Jin Ho Hwang, MD, PhD, Chung-Ang University College of Medicine, South Korea

Jin Ho Hwang is an assistant professor in the Department of Internal Medicine at Chung-Ang University College of Medicine, and a nephrologist of Chung-Ang University Hospital in South Korea. She has conducted research on alleviating renal fibrosis, electrolyte imbalance, substances that cause nephrotoxicity, and hemodynamic factors causing acute kidney injury. She has been an Editorial Board Member for Scientific Reports since 2024.

 

Akira Mima, MD, PhD, Osaka Medical and Pharmaceutical University, Japan

Akira Mima is a Professor of the Department of Nephrology at Osaka Medical and Pharmaceutical University, Osaka, Japan. He is engaged in research on the mechanisms of progression and exacerbation of diabetic kidney disease and chronic kidney disease and on dialysis therapy. he has been an Editorial Board Member for Scientific Reports since 2024.