Collection 

Chronic kidney disease

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Chronic kidney disease (CKD) describes several conditions characterised by progressive kidney damage and loss of function. CKD is known to affect millions worldwide and is growing in prevalence due to a rise in the population effected by major risk factors, including obesity, diabetes, and ageing. Causes can be both environmental and genetic, with the most common being diabetes, hypertension, and glomerulonephritis.

The disease is classified into 5 stages based on the severity of the abnormal reduction in glomerular filtration rate a patient experiences. At the early stages (1-3), patients have mild to moderate loss of kidney function, whereas stage 5 is also known as end stage renal disease and patients at this stage will most likely require kidney transplant.

Early diagnosis is vital to slow disease progression and to ensure patient quality of life is preserved as much as possible, however, with patients often displaying limited symptoms during the early stages of the disease, many may be unaware of their condition until it is advanced.

This Collection aims to bring together primary research papers that describe methods for improved CKD early diagnosis, monitoring or treatment or provide mechanistic insight into the underlying causes of the disease.

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Collections articles undergo Scientific Reports' standard peer review process and are subject to all of the journal’s standard policies. This includes the journal’s policy on competing interests. The Guest Editors have no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Guest Editors have competing interests is handled by another Editorial Board Member who has no competing interests. For more information, refer to our Collections guidelines.

This Collection has not been supported by sponsorship.