Mitochondrial function and metabolic health
- Submission status
- Open
- Submission deadline
Mitochondria are central hubs in a diversity of processes, including cellular energy metabolism, immunity, and signal transduction. Due to their function at the heart of cellular energy metabolism, the healthy functioning of our mitochondria is vitally important for overall metabolic health. As dynamic organelles, mitochondria can adapt to energetic, environmental, and other stressors, but also malfunction in a variety of ways. Evidence suggests that mitochondrial dysfunction may occur early in disease pathology, and has the potential to be modulated by genetics, environment, and lifestyle. Although a major factor in many disease states, an understanding of the precise involvement of mitochondria in the aetiology and prevention of metabolic disease will lead to further discoveries in this field.
This collection aims to cover a broad range of themes linking mitochondrial function to metabolic health and disease outcomes. We seek to gain further understanding of both the mechanisms that govern mitochondrial function, and how changes to mitochondrial function impact on a wide spectrum of metabolic health and disease including metabolic-associated diseases such as obesity and type 2 diabetes, but also cancer, exercise capacity, cardiometabolic health and longevity. In addition, therapeutic treatments that target mitochondrial mechanisms and processes will be of interest in this special collection.
The topics include but are not limited to:
• Bioenergetics
• Mitochondrial regulation
• Mitochondrial redox biology
• Mitochondrial structural remodelling and dynamics
• Mitophagy
• Mitochondrial disease
• Mitochondrial biogenesis
• Mitochondrial genome
• Interventions targeting mitochondria
Editors
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Brenna Osborne, PhD
University of Copenhagen, Denmark
The Collection will publish original research Articles, and Commentary such as Reviews, Perspectives, and Comments (full details on content types can be found here). Papers will be published in npj Metabolic Health and Disease as soon as they are accepted and then collected together and promoted on the Collection homepage. All Guest Edited Collections are associated with a call for papers and are managed by one or more of our Editorial Board Members and the journal's Editors.
This Collection welcomes submissions from all authors – and not by invitation only – on the condition that the manuscripts fall within the scope of the Collection and of npj Metabolic Health and Disease more generally. See our editorial process page for more details.
All submissions are subject to the same peer review process and editorial standards as regular npj Metabolic Health and Disease articles, including the journal’s policy on competing interests. The Guest Editor has no competing interests with the submissions, which she handles through the peer-review process. The peer review of any submissions for which the Guest Editor has competing interests is handled by another Editorial Board Member who has no competing interests. See our Collections guidelines for more details.
This Collection is not supported by sponsorship.
