Aims & Scope

npj Metabolic Health and Disease considers all aspects of metabolism, including the basic mechanisms of metabolism and metabolic diseases, as well as pre-clinical and clinical studies focussing on diagnostic tools, effects of interventions for the prevention and treatment of metabolic pathophysiology, epidemiology, public health, and global health. 

The journal covers a broad range of topics including but not limited to: 

  • Type 1 and type 2 diabetes pathophysiology, management, and complications
  • Molecular mechanisms and therapeutic approaches to insulin resistance 
  • Obesity etiology, mechanisms, interventions, and associated comorbidities
  • Metabolic syndrome diagnosis, risk factors, and treatment 
  • Adipose tissue biology, metabolism, and dysfunction
  • Lipid metabolism regulation, dyslipidemia, and cardiovascular risk
  • Genetic and epigenetic factors in metabolic health and disease
  • Liver metabolism and associated metabolic diseases 
  • Cardiovascular disease and associated metabolic dysfunction
  • Cancer metabolism
  • Gut microbiota and metabolic health
  • Influence of nutrition and physical activity on metabolic health and disease
  • Nutrient sensing and substrate metabolism 
  • Endocrine regulation of metabolism, including hormones, receptors, and signaling pathways
  • Cellular and mitochondrial metabolism
  • Pharmacotherapy and new therapies for metabolic diseases

The journal offers more choice to Nature Portfolio authors who are seeking a fully open-access and more inclusive platform for publishing their work. The journal is led by metabolic health experts who collaborate to cultivate high-quality research. As part of the npj Series, this journal focuses on fostering global partnerships with the research community and other Springer Nature journals.