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Biomedical Genomics Series - Cancer
The Journal of Human Genetics is delighted to present the latest from the Series on Biomedical Genomics, a Web Focus on Cancer. The Focus includes reports covering genetic research into identifying risk and associations with Breast Cancer, lung squamous cell carcinoma, adenocarcinoma, and cervical cancer in different populations, such as Korean, Chinese, Japanese and Amerindian.
Original Articles
Tumor suppressive microRNA-375 regulates oncogene AEG-1/MTDH in head and neck squamous cell carcinoma (HNSCC) FREE
Nijiro Nohata, Toyoyuki Hanazawa, Naoko Kikkawa, Muradil Mutallip, Daiju Sakurai, Lisa Fujimura, Kazumori Kawakami, Takeshi Chiyomaru, Hirofumi Yoshino, Hideki Enokida, Masayuki Nakagawa, Yoshitaka Okamoto and Naohiko Seki
J Hum Genet 56: 595-601; advance online publication, July 14, 2011; doi:10.1038/jhg.2011.66
MicroRNA-141 confers resistance to cisplatin-induced apoptosis by targeting YAP1 in human esophageal squamous cell carcinoma FREE
Yukako Imanaka, Soken Tsuchiya, Fumiaki Sato, Yutaka Shimada, Kazuharu Shimizu and Gozoh Tsujimoto
J Hum Genet 56: 270-276; advance online publication, February 3, 2011; doi:10.1038/jhg.2011.1
Tumor suppressive microRNA-133a regulates novel molecular networks in lung squamous cell carcinoma FREE
Yasumitsu Moriya, Nijiro Nohata, Takashi Kinoshita, Muradil Mutallip, Tatsuro Okamoto, Shigetoshi Yoshida, Makoto Suzuki, Ichiro Yoshino and Naohiko Seki
J Hum Genet 57: 38-45; advance online publication, November 17, 2011; doi:10.1038/jhg.2011.126
KEAP1 gene mutations and NRF2 activation are common in pulmonary papillary adenocarcinoma FREE
Qing Kay Li, Anju Singh, Shyam Biswal, Frederic Askin and Edward Gabrielson
J Hum Genet 56: 230-234; advance online publication, January 20, 2011; doi:10.1038/jhg.2010.172
Spectra of BRCA1 and BRCA2 mutations in Korean patients with breast cancer: the importance of whole-gene sequencing FREE
Ja-Hyun Jang, Jeong Eon Lee, Min-Jung Kwon, Chang-Seok Ki, Jong-Won Kim, Seok Jin Nam and Jung-Hyun Yang
J Hum Genet 57: 212-215; advance online publication, January 5, 2012; doi:10.1038/jhg.2011.139
Functional single-nucleotide polymorphism of epidermal growth factor is associated with the development of Barrett's esophagus and esophageal adenocarcinoma FREE
Vivianda Menke, Raymond GJ Pot, Leon MG Moons, Katinka PM van Zoest, Bettina Hansen, Herman van Dekken, Peter D Siersema, Johannes G Kusters and Ernst J Kuipers
J Hum Genet 57: 26-32; advance online publication, December 1, 2011; doi:10.1038/jhg.2011.124
Composite likelihood-based meta-analysis of breast cancer association studies FREE
Ioannis Politopoulos, Jane Gibson, William Tapper, Sarah Ennis, Diana Eccles and Andrew Collins
J Hum Genet 56: 377-382; advance online publication, March 10, 2011; doi:10.1038/jhg.2011.23
Genetic variants at 5p12 and risk of breast cancer in Han Chinese FREE
Xiao'an Liu, Zhenzhen Qin, Hao Shen, Jialei Xue, Yue Jiang, Zhibin Hu, Hongbing Shen and Shui Wang
J Hum Genet 57: 638-641; advance online publication, July 26, 2012; doi:10.1038/jhg.2012.83
The functional significance of microRNA-375 in human squamous cell carcinoma: aberrant expression and effects on cancer pathways FREE
Takashi Kinoshita, Toyoyuki Hanazawa, Nijiro Nohata, Yoshitaka Okamoto and Naohiko Seki
J Hum Genet 57: 556-563; advance online publication, June 21, 2012; doi:10.1038/jhg.2012.75
A genome-wide association study identifies SNP in DCC is associated with gallbladder cancer in the Japanese population FREE
Pei-Chieng Cha, Hitoshi Zembutsu, Atsushi Takahashi, Michiaki Kubo, Naoyuki Kamatani and Yusuke Nakamura
J Hum Genet 57: 235-237; advance online publication, February 9, 2012; doi:10.1038/jhg.2012.9
The Amerindian mtDNA haplogroup B2 enhances the risk of HPV for cervical cancer: de-regulation of mitochondrial genes may be involved FREE
Mariano Guardado-Estrada, Ingrid Medina-Martínez, Eligia Juárez-Torres, Edgar Roman-Bassaure, Luis Macías, Ana Alfaro, Avissai Alcántara-Vázquez, Patricia Alonso, Guillermo Gomez, Fernando Cruz-Talonia, Luis Serna, Sergio Muñoz-Cortez, Manuel Borges-Ibañez, Ana Espinosa, Susana Kofman and Jaime Berumen
J Hum Genet 57: 269-276; advance online publication, February 23, 2012; doi:10.1038/jhg.2012.17
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