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The ECCO 2019 European Cancer Summit on 12-14 September 2019 in Brussels, Belgium will bring together worldwide leaders from cancer care, research, patient advocacy and public-private sectors in a unique multi-stakeholder forum. The theme of the second edition of the ECCO Summit is: “European Cancer Care: Across Borders”. The Editor-in-Chief of Cancer Gene Therapy, in the spirit of this important event, is pleased to showcase the work of many researchers in this field, which align with the critical themes of this exciting congress.