Recent achievements in development of cell death-based approaches to treatment of various diseases are summarized in this collection of articles from Cell Death & Disease. Disturbances in cell death pathways at the molecular level are linked to the pathogenesis of various diseases. Evidence suggests that suppression or activation of one type of cell death can influence the activity of another, which in turn can affect the response of cells to therapy. We hope that this collection attracts attention to this growing area of research, and encourages the further exploitation of cell death mechanisms in the development of new treatments for human disease.

In this Web Focus, we report some recently published papers about p53 in our journals.We hope that this selection is of interest to our readers.

A web focus from Cell Death & Differentiation, Cell Death & Disease, Nature Immunology and Oncogene. We hope you enjoy this focus including work from the world's most recognized experts in the field of Necroptosis.

A web focus from Cell Death & Differentiation and Cell Death & Disease. We hope you enjoy this focus including work from the world's most recognized experts in the field of Alzheimer's disease.

Cell Death & Disease is delighted to announce it has published its 1000th article: ''The traditional Chinese medical compound Rocaglamide protects non-malignant primary cells from DNA damage-induced toxicity by inhibition of p53 expression.'' To mark this achievement, we have published the following web focus from Cell Death & Disease and Cell Death & Differentiation on anti-cancer therapies. We hope you enjoy this focus including work from the world's most recognized experts in the field of anti-cancer therapies.

The Editors of Cell Death & DifferentiationandCell Death & Diseaseare delighted to share with you a selection of key papers that highlight some of the best work published in the journals over recent years and which also showcase the breadth of scope and coverage that these journals consistently deliver to their readers. We hope you enjoy reading these papers as much as we have!

The Editors of Cell Death & DifferentiationandCell Death & Diseaseare delighted to share with you a selection of key papers that highlight some of the best work published in the journals over recent years and which also showcase the breadth of scope and coverage that these journals consistently deliver to their readers. We hope you enjoy reading these papers as much as we have!

A web focus from Cell Death & Differentiation and Cell Death & Disease. We hope you enjoy this focus including work from the world's most recognized experts in the field of Computational Cell Death and Bioinformatics.

A web focus from Cell Death & Differentiation and Cell Death & Disease. We hope you enjoy this focus including work from the world's most recognized experts in the field of Diabetes.

A web focus from Cell Death & Differentiation and Cell Death & Disease. We hope you enjoy this focus including work from the world's most recognized experts in the field of Parkinson’s disease.

A web focus from Cell Death & Differentiation,Cell Death & DiseaseandNature Communications. Recent progress in cell death, stem cell biology and cancer research has created a new paradigm of research direction, shifting from pure analytical approaches toward a more translational one with animals and patients. The purpose of this focus is to cover a variety of important topics in cancer and immunology research under the main theme: "Cell Death, Stem Cell and Immunology."

A web focus from Cell Death & Differentiation and Cell Death & Disease. This web collection is published in conjunction with the 21st ECDO Euroconference on Apoptosis entitled 'Cell death: a Biomedical paradigm'. This annual international meeting addresses a wide range of questions on the normal regulation and pathogenic dysfunction of distinct cell death modalities, the new strategies for therapeutic cancer cell induction, and the immunogenicity of distinct cell death types.