FOCUS
CDDIS Editors’ Picks
The Editors of Cell Death & Differentiation and Cell Death & Disease are delighted to share with you a selection of key papers that highlight some of the best work published in the journals over recent years and which also showcase the breadth of scope and coverage that these journals consistently deliver to their readers. We hope you enjoy reading these papers as much as we have!
IMMUNITY
Minocycline selectively inhibits M1 polarization of microglia Open
K Kobayashi, S Imagama, T Ohgomori, K Hirano, K Uchimura, K Sakamoto, A Hirakawa, H Takeuchi, A Suzumura, N Ishiguro and K Kadomatsu
Cell Death and Disease 4: e525; Published online, 07 March 2013; doi:10.1038/cddis.2013.54
Blockade of BFA-mediated apoptosis in macrophages by the HIV-1 Nef protein Open
W Abbas, K A Khan, A Kumar, M K Tripathy, I Dichamp, M Keita, U Mahlknecht, O Rohr and G Herbein
Cell Death and Disease 5: e1080; Published online, 20 February 2014; doi:10.1038/cddis.2014.16
Survivin-2B promotes autophagy by accumulating IKK alpha in the nucleus of selenite-treated NB4 cells Open
K Shi, J An, L Shan, Q Jiang, F Li, Y Ci, P Wu, J Duan, K Hui, Y Yang and C Xu
Cell Death and Disease 5: e1071; Published online, 20 February 2014; doi:10.1038/cddis.2014.34
CANCER
Targeting cellular metabolism to improve cancer therapeutics Open
Y Zhao, E B Butler and M Tan
Cell Death and Disease 4: e532; Published online, 07 March 2013; doi:10.1038/cddis.2013.60
MiR-210 promotes a hypoxic phenotype and increases radioresistance in human lung cancer cell lines Open
S Grosso, J Doyen, S K Parks, T Bertero, A Paye, B Cardinaud, P Gounon, S Lacas-Gervais, A Noël, J Pouysségur, P Barbry, N M Mazure and B Mari
Cell Death and Disease 4: e544; Published online, 14 March 2013; doi:10.1038/cddis.2013.71
PTEN-regulated AKT/FoxO3a/Bim signaling contributes to reactive oxygen species-mediated apoptosis in selenite-treated colorectal cancer cells Open
H Luo, Y Yang, J Duan, P Wu, Q Jiang and C Xu
Cell Death and Disease 4: e481; Published online, 07 February 2013; doi:10.1038/cddis.2013.3
miR-129 promotes apoptosis and enhances chemosensitivity to 5-fluorouracil in colorectal cancer Open
M Karaayvaz, H Zhai and J Ju
Cell Death and Disease 4: e659; Published online, 06 June 2013; doi:10.1038/cddis.2013.193
Wnt activation promotes neuronal differentiation of Glioblastoma Open
E Rampazzo, L Persano, F Pistollato, E Moro, C Frasson, P Porazzi, A Della Puppa, S Bresolin, G Battilana, S Indraccolo, G Te Kronnie, F Argenton, N Tiso and G Basso
Cell Death and Disease 4: e500; Published online, 21 February 2013; doi:10.1038/cddis.2013.32
MEDICINE
Molecular mechanisms of hepatic apoptosis Open
K Wang
Cell Death and Disease 5: e996; Published online, 16 January 2014; doi:10.1038/cddis.2013.499
Histone modifications are responsible for decreased Fas expression and apoptosis resistance in fibrotic lung fibroblasts Open
S K Huang, A M Scruggs, J Donaghy, J C Horowitz, Z Zaslona, S Przybranowski, E S White and M Peters-Golden
Cell Death and Disease 4: e621; Published online, 02 May 2013; doi:10.1038/cddis.2013.146
Redundant miR-3077-5p and miR-705 mediate the shift of mesenchymal stem cell lineage commitment to adipocyte in osteoporosis bone marrow Open
L Liao, X Yang, X Su, C Hu, X Zhu, N Yang, X Chen, S Shi, S Shi, Y Jin
Cell Death and Disease 4: e600; Published online, 18 April 2013; doi:10.1038/cddis.2013.130
TNF can activate RIPK3 and cause programmed necrosis in the absence of RIPK1 Open
D M Moujalled, W D Cook, T Okamoto, J Murphy, K E Lawlor, J E Vince and D L Vaux
Cell Death and Disease 4: e465; Published online, 17 January 2013; doi:10.1038/cddis.2012.201
TGF-β1 exposure induces epithelial to mesenchymal transition both in CSCs and non-CSCs of the A549 cell line, leading to an increase of migration ability in the CD133+ A549 cell fraction Open
V Tirino, R Camerlingo, K Bifulco, E Irollo, R Montella, F Paino, G Sessa, M V Carriero, N Normanno, G Rocco and G Pirozzi
Cell Death and Disease 4: e620; Published online, 02 May 2013; doi:10.1038/cddis.2013.144
NEUROSCIENCE
The evolutionary young miR-1290 favors mitotic exit and differentiation of human neural progenitors through altering the cell cycle proteins Open
S V Yelamanchili, B Morsey, E B Harrison, D A Rennard, K Emanuel, I Thapa, D R Bastola and H S Fox
Cell Death and Disease 5: e982; Published online, 09 January 2014; doi:10.1038/cddis.2013.498
Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson’s disease Open
A C Costa, S H Y Loh and L Miguel Martins
Cell Death and Disease 4: e467; Published online, 17 January 2013; doi:10.1038/cddis.2012.205
Calcium-activated and apoptotic phospholipid scrambling induced by Ano6 can occur independently of Ano6 ion currents Open
A Kmit, R van Kruchten, J Ousingsawat, N J A Mattheij, B Senden-Gijsbers, J W M Heemskerk, R Schreiber, E M Bevers and K Kunzelmann
Cell Death and Disease 4: e611; Published online, 25 April 2013; doi:10.1038/cddis.2013.135
NMDA receptor subunit composition determines beta-amyloid-induced neurodegeneration and synaptic loss Open
C Tackenberg, S Grinschgl, A Trutzel, A C Santuccione, M C Frey, U Konietzko, J Grimm, R Brandt and R M Nitsch
Cell Death and Disease 4: e608; Published online, 25 April 2013; doi:10.1038/cddis.2013.129
METABOLISM
Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP+ Open
A K Krug, S Gutbier, L Zhao, D Pöltl, C Kullmann, V Ivanova, S Förster, S Jagtap, J Meiser, G Leparc, S Schildknecht, M Adam, K Hiller, H Farhan, T Brunner, T Hartung, A Sachinidis and M Leist
Cell Death and Disease 5: e1222; Published online, 08 May 2014; doi:10.1038/cddis.2014.166
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