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Feeding regulation

Daily feeding entrains hunger-sensing neurons

Neuroscientists have long believed that hunger increases activity in agouti-related peptide (AgRP) neurons to regulate feeding-related behaviors and metabolism, but a new study shows that the story is much more complicated. Sayar-Atasoy and colleagues show that the time of day uncouples activity in AgRP neurons from hunger and demonstrate how daily feeding patterns influence future AgRP neuron activity.

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Fig. 1: Daily feeding entrains hunger-sensing neurons.

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Correspondence to Zane B. Andrews.

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Andrews, Z.B. Daily feeding entrains hunger-sensing neurons. Nat Neurosci 27, 10–12 (2024). https://doi.org/10.1038/s41593-023-01508-z

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