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Osteoarthritis

Treg cell-inducing nanoparticles show promise for treating OA

Nature Reviews Rheumatology volume 19, page 62 (2023)Cite this article

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Evidence increasingly implicates low-grade inflammation as an important mediator of osteoarthritis (OA) pathogenesis, opening up potential immunomodulatory therapeutic strategies for this disease. New findings highlight modulation of regulatory T (Treg) cells by nanoparticles as one such promising approach.

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References

Original article

  • Sohn, H. S. et al. Tolerogenic nanoparticles induce type II collagen–specific regulatory T cells and ameliorate osteoarthritis. Sci. Adv. 8, eabo5284 (2022)

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  1. Nature Reviews Rheumatology http://www.nature.com/nrrheum/

    Jessica McHugh

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  1. Jessica McHugh
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Correspondence to Jessica McHugh.

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McHugh, J. Treg cell-inducing nanoparticles show promise for treating OA. Nat Rev Rheumatol 19, 62 (2023). https://doi.org/10.1038/s41584-023-00906-8

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  • DOI: https://doi.org/10.1038/s41584-023-00906-8

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