Notch signaling in the pathogenesis of the Tetralogy of Fallot represents a puzzle interacting with many components.1 If we put all its components together, the result will be a structurally and functionally normal heart, but if one or several details fall out, it will be impossible to get a complete picture. Coordinated action of Notch genes is a very important component of this puzzle. 
Reference
Kozyrev, I. et al. Dysregulation of Notch signaling in cardiac mesenchymal cells of patients with tetralogy of Fallot. Pediatr. Res. https://doi.org/10.1038/s41390-020-0760-6 (2020).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Kozyrev, I., Dokshin, P., Kostina, A. et al. Insights Image for “Dysregulation of Notch signaling in cardiac mesenchymal cells of patients with Tetralogy of Fallot”. Pediatr Res 88, 139 (2020). https://doi.org/10.1038/s41390-020-0848-z
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41390-020-0848-z
