Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Practice Point
  • Published:

Does adjuvant chemoradiation benefit patients who have undergone resection of pancreatic or periampullary cancer?

Nature Clinical Practice Gastroenterology & Hepatology volume 5, pages 364–365 (2008)Cite this article

boxed-textSmeenk HG et al. (2007) Long-term survival and metastatic pattern of pancreatic and periampullary cancer after adjuvant chemoradiation or observation: long-term results of the EORTC trial 40891. Ann Surg 246: 734–740

The optimal adjuvant therapy for patients who have undergone resection of pancreatic or periampullary cancer is not clear; further, well-designed, randomized, controlled trials are required

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Jemal A et al. (2007) Cancer statistics, 2007. CA Cancer J Clin 57: 43–66

    Article  Google Scholar 

  2. Gastrointestinal Tumor Study Group (1987) Further evidence of effective adjuvant combined radiation and chemotherapy following curative resection of pancreatic cancer. Cancer 59: 2006–2010

  3. Neoptolemos JP et al. (2001) Adjuvant chemoradiotherapy and chemotherapy in resectable pancreatic cancer: a randomised controlled trial. Lancet 358: 1576–1585

    Article  CAS  Google Scholar 

  4. Regine WF et al. (2008) Fluorouracil vs gemcitabine chemotherapy before and after fluorouracil-based chemoradiation following resection of pancreatic adenocarcinoma. A Randomized Controlled Trial. JAMA 299: 1019–1026

    Article  CAS  Google Scholar 

Download references

Acknowledgements

The synopsis was written by Rachel Jones, Associate Editor, Nature Clinical Practice.

Author information

Authors and Affiliations

  1. in the Department of Radiation Oncology at the Duke University Medical Center, CG Willett is the Leonard R Prosnitz Professor and Chair, and BG Czito is Associate Professor, Durham, NC, USA.,

    Christopher G Willett & Brian G Czito

Authors
  1. Christopher G Willett
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Brian G Czito
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Christopher G Willett.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Willett, C., Czito, B. Does adjuvant chemoradiation benefit patients who have undergone resection of pancreatic or periampullary cancer?. Nat Rev Gastroenterol Hepatol 5, 364–365 (2008). https://doi.org/10.1038/ncpgasthep1152

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/ncpgasthep1152

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing