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References
Nestorov I (2005) Clinical pharmacokinetics of TNF antagonists: how do they differ? Semin Arthritis Rheum 34 (Suppl 1): 12–18
Targan SR et al. (1997) A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group. N Engl J Med 337: 1029–1035
Sandborn W et al. (2004) An open-label study of the human anti-TNF monoclonal antibody adalimumab in subjects with prior loss of response or intolerance to infliximab for Crohn's disease. Am J Gastroenterol 99: 1984–1989
Bongartz T et al. (2006) Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: systematic review and meta-analysis of rare harmful effects in randomized controlled trials. JAMA 295: 2275–2285
Anderson PJ (2005) Tumor necrosis factor inhibitors: clinical implications of their different immunogenicity profiles. Semin Arthritis Rheum 34 (Suppl 1): 19–22
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The synopsis was written by Rachel Jones, Associate Editor, Nature Clinical Practice.
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The author has declared associations with the following companies: Abbott, Schering Plough, Centocor and UCB.The author has been a member of the advisory board of Abbott, Schering Plough, Centocor and UCB. He has received honorarium for lecturing in conferences sponsored by Schering Plough and UCB. The author has also received funding from Schering Plough to support research.
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Ghosh, S. How effective is adalimumab for inducing remission in patients with moderate-to-severe Crohn's disease?. Nat Rev Gastroenterol Hepatol 3, 540–541 (2006). https://doi.org/10.1038/ncpgasthep0605
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DOI: https://doi.org/10.1038/ncpgasthep0605