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Is esomeprazole an effective therapy for patients with GERD who have night-time heartburn?

Nature Clinical Practice Gastroenterology & Hepatology volume 3, pages 128–129 (2006)Cite this article

boxed-textJohnson DA et al. (2005) Effect of esomeprazole on nighttime heartburn and sleep quality in patients with GERD: a randomized placebo-controlled trial. Am J Gastroenterol 100: 1914–1922

Physicians should question patients with GERD about nocturnal symptoms, because those symptoms are frequent, harmful, and responsive to antisecretory therapy

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References

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Acknowledgements

The synopsis was written by Rachel Jones, Associate Editor, Nature Clinical Practice.

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Authors and Affiliations

  1. Division of Gastroenterology at the Dallas Department of Veterans Affairs Medical Center,

    Stuart J Spechler

  2. University of Texas Southwestern Medical Center at Dallas, TX, USA

    Stuart J Spechler

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  1. Stuart J Spechler
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Correspondence to Stuart J Spechler.

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Competing interests

Dr Spechler has received grant support from AstraZeneca, TAP Pharmaceuticals and CDx Laboratories. He is also a member of the speaker's bureau for AstraZeneca, TAP and Janssen.

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Spechler, S. Is esomeprazole an effective therapy for patients with GERD who have night-time heartburn?. Nat Rev Gastroenterol Hepatol 3, 128–129 (2006). https://doi.org/10.1038/ncpgasthep0419

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